Impact of academic collaboration and quality of clinical orthopaedic research conducted in low- and middle-income countries

Wu, Hao-Hua; Liu, Max; Patel, Karan; Turner, Wes; Baltus, Lincoln; Caldwell, Amber; Hahn, Jesse C.; Coughlin, Ralph Richard; Morshed, Saam; Miclau, Theodore; Shearer, David

doi:10.1051/sicotj/2016042

Cited by 21 publications

(15 citation statements)

References 22 publications

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“…Only 10% of the 132 publications from LICs were classified as level I or II evidence, with the majority of articles being case series or level IV evidence. Our findings mirror that of a recent study reported by Wu et al [18], who found that only 10% of the studies from LMICs evaluated reported level I or II evidence but that when investigators in LMICs and from HICs collaborated, research was of a higher evidence quality [18]. The present study similarly found that of the nine articles that were classed as high-level evidence, 78% ( n = 7) were collaborative articles.…”

Section: Discussionsupporting

confidence: 89%

Orthopaedic research in low-income countries: A bibliometric analysis of the current literature

Graham

Brennan

Laubscher

et al. 2019

SICOT-J

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Background: To perform a bibliometric analysis and quantify the amount of orthopaedic and trauma literature published from low-income countries (LICs).Methods and methods: The Web of Science database was utilised to identify all indexed orthopaedic journals. All articles published in the 76 orthopaedics journals over the last 10 years were reviewed, to determine their geographic origin.Results: A total of 131 454 articles were published across 76 orthopaedic journals over the last 10 years. Of these, 132 (0.1%) were published from LICs and 3515 (2.7%) were published from lower middle-income countries (LMICs); 85.7% (n = 112 716) of published orthopaedic research was undertaken in a high-income setting. The majority of the studies (n = 90, 74.4%) presented level IV evidence. Only 7.4% (n = 9) were high-quality evidence (level I or II). Additionally, the majority of research (74 articles, 56%) was published in partnership with high-income countries (HICs).Conclusions: There is a stark mismatch between the publication of scientific reports on orthopaedic research and the geographical areas of greatest clinical need. We believe there is an urgent need for orthopaedic research to be carried out in low-income settings to guide treatment and improve outcomes, rather than assuming that evidence from high-income settings will translate into this environment. Level of evidence: IV

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Section: Discussionsupporting

confidence: 89%

Orthopaedic research in low-income countries: A bibliometric analysis of the current literature

Graham

Brennan

Laubscher

et al. 2019

SICOT-J

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“…Limited evidence is available on the perception of the importance of research quality in capacity building studies from the MENA region. Approaches to increase research quality in other fields such as orthopaedic research in LMICs identified academic collaboration, defined as the inclusion of LMIC and non-LMIC investigator, to be associated with higher levels of evidence and thus higher quality studies [ 28 ]. In cancer treatment trials, international and national academic collaboration is supported by a way to improve cancer therapy and patient outcomes [ 29 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

Mapping breast cancer journal publications in conflict settings in the MENA region: a scoping review

Abdul-Khalek¹,

Abu-Sitta²,

Achi³

et al. 2020

ecancer

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Background: Breast cancer is a major cause of cancer-related morbidity and mortality among women in the the Middle East and North Africa (MENA) region. Conflict and political instability in the region may affect medical research output, including that on breast cancer. This scoping review aims to systematically identify and map breast cancer publications across different stages of the cancer care pathway and across conflict-affected countries within the MENA region. The findings of this work will highlight the impact of conflict on cancer research that could be mitigated with the proper contextualised capacity strengthening intervention. Methods: We followed the PRISMA-Scr methodology. We searched for peer-reviewed publications on topics related to breast cancer in 11 databases: Medline, PubMed, EMBASE, Web of Science, PROQUEST, CINAHL, Global Index Medicus, Arab World Searches Complete, Popline, Scopus and Google Scholar using both controlled vocabulary and keywords. Publication abstracts and full-text versions were screened for duplicates and included in our study based on pre-specified eligibility criteria: focused on breast cancer, related to the specific country of analysis and human or health system studies. We used a structured data extraction form to extract information related to the article, its methodology and the cancer care pathway being studied. Results: A total of 19,215 citations were retrieved from our search. After removing duplicates, a total of 8,622 articles remained. Title and abstract screening retained 1,613 articles. Publications with first author affiliations to Turkey were consistently the highest across all categories of the cancer care pathway. Trends show an increase in articles from Lebanon, Jordan and Palestine after 2015. Early exploratory and epidemiological studies represented the majority of breast cancer research, followed by policy and implementation research and lastly experimental research. Most research conducted followed an observational study design. Important gaps were identified in the research output related to advanced breast cancer and palliative care (Libya, Syria and Yemen), mental health (Libya), and knowledge and education of breast cancer (Libya and Syria). Conclusion: This scoping review has identified key areas in breast cancer research that lack significant research activity in conflict MENA settings. These areas, including but are not limited to palliative care, mental health, and education, can be prioritised and developed through regional collaboration and contextualised capacity strengthening initiatives.

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“…Not only are locally relevant questions answered but a culture of research and critical assessment of outcomes is also fostered in an environment that trains future leaders. Our prior work has demonstrated the positive effects of collaboration on the quality of clinical research generated in LMICs ( 28 ).…”

Section: Methodological Aspectsmentioning

confidence: 99%

The Institute for Global Orthopedics and Traumatology: A Model for Academic Collaboration in Orthopedic Surgery

Conway

Coughlin

Caldwell

et al. 2017

Front. Public Health

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In 2006, surgeons at the University of California, San Francisco (UCSF) established the Institute for Global Orthopedics and Traumatology (IGOT), an initiative within the department of orthopedic surgery. The principal aim of IGOT is to create long-term, sustainable solutions to the growing burden of musculoskeletal injury in low- and middle-income countries (LMICs) through academic partnership. IGOT currently has relationships with teaching hospitals in Ghana, Malawi, Tanzania, Nicaragua, and Nepal. The organizational structure of IGOT is built on four pillars: Global Surgical Education (GSE), Global Knowledge Exchange (GKE), Global Research Initiative (GRI), and Global Leadership and Advocacy. GSE focuses on increasing surgical knowledge and technical proficiency through hands-on educational courses. The GKE facilitates the mutual exchange of surgeons and trainees among IGOT and its partners. This includes a global resident elective that allows UCSF residents to complete an international rotation at one of IGOT’s partner sites. The GRI strives to build research capacity and sponsor high-quality clinical research projects that address questions relevant to local partners. The fourth pillar, Global Leadership and Advocacy aims to increase awareness of the global impact of musculoskeletal injury through national and international courses and events, such as the Bay Area Global Health Film Festival. At the core of each tenet is the collaboration among IGOT and its international partners. Over the last decade, IGOT has experienced tremendous growth and maturation in its partnership model based on cumulative experience and the needs of its partners.

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Impact of academic collaboration and quality of clinical orthopaedic research conducted in low- and middle-income countries

Cited by 21 publications

References 22 publications

Orthopaedic research in low-income countries: A bibliometric analysis of the current literature

Orthopaedic research in low-income countries: A bibliometric analysis of the current literature

Mapping breast cancer journal publications in conflict settings in the MENA region: a scoping review

The Institute for Global Orthopedics and Traumatology: A Model for Academic Collaboration in Orthopedic Surgery

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