2024
DOI: 10.1002/jpn3.12389
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Impact of acid blocker therapy on growth, gut microbiome, and lung disease in young children with cystic fibrosis

Cathy Liu,
Taiya R. Bach,
Philip M. Farrell
et al.

Abstract: ObjectiveAcid blocker therapy (ABT) has become common in cystic fibrosis (CF), despite insufficient evidence for benefits and studies showing potentially negative effects. We examined associations between ABT usage and growth, gut microbiome (GM), and early‐onset lung disease in young children with CF.MethodsOne hundred forty‐five infants with CF born during 2012–2017, diagnosed through newborn screening by age 3 months and followed to 36 months of age at six CF centers were evaluated. Longitudinal data on gro… Show more

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