Impact of air pollution on human health in different geographical locations of Nepal

Giri, Jyoti; Raut, Sweccha; Rimal, Binita; Adhikari, Rameshwar; Joshi, Tista Prasai; Shah, Ganesh

doi:10.1016/j.envres.2023.115669

Cited by 7 publications

(1 citation statement)

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“…Most previous studies have focused solely on participants in plain regions to estimate the association between ambient air pollutants and hypertension [ 18 , 19 ], which may have resulted in a limited understanding of the comprehensive impacts of ambient air pollution on hypertension among residents of high-altitude areas [ 20 , 21 ]. Intuitively, individuals residing at higher altitudes appear to face a lower risk of hypertension, as they are exposed to lower levels of air pollution compared to those living at lower altitudes.…”

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confidence: 99%

Long-term exposure to particulate matter is associated with elevated blood pressure: Evidence from the Chinese plateau area

Li,

Yu,

Yin

et al. 2024

J Glob Health

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Background Ambient air pollution could increase the risk of hypertension; however, evidence regarding the relationship between long-term exposure to particulate matter and elevated blood pressure in plateau areas with lower pollution levels is limited. Methods We assessed the associations of long-term exposure to particulate matter (PM, PM 1 , PM 2.5 , and PM 10 ) with hypertension, diastolic blood pressure (DBP), systolic blood pressure (SBP) and pulse pressure (PP) in 4.235 Tibet adults, based on the baseline of the China multi-ethnic cohort study (CMEC) in Lhasa city, Tibet from 2018–19. We used logistic regression and linear regression models to evaluate the associations of ambient PM with hypertension and blood pressure, respectively. Results Long-term exposure to PM 1 , PM 2.5 , and PM 10 is positively associated with hypertension, DBP, and SBP, while negatively associated with PP. Among these air pollutants, PM 10 had the strongest effect on hypertension, DBP, and SBP, while PM 2.5 had the strongest effect on PP. The results showed for hypertension odds ratio (OR) = 1.99; 95% confidence interval (CI) = 1.58, 2.51 per interquartile range (IQR) μg/m 3 increase in PM 1 , OR = 1.93; 95% CI = 1.55, 2.40 per IQR μg/m 3 increase in PM 2.5 , and OR = 2.12; 95% CI = 1.67, 2.68 per IQR μg/m 3 increase in PM 10 . Conclusions Long-term exposure to ambient air pollution was associated with an increased risk of hypertension, elevated SBP and DBP levels, and decreased PP levels. To reduce the risk of hypertension and PP reduction, attention should be paid to air quality interventions in plateau areas with low pollution levels.

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confidence: 99%