Impact of alcohol &amp; smoking on the surgical management of gastrointestinal patients

Kennedy, Niall; Winter, D. C.

doi:10.1016/j.bpg.2017.10.005

Cited by 5 publications

(11 citation statements)

References 108 publications

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“…Moreover, a history of alcohol consumption is an in uential factor in the development of postoperative complications that clinicians should not forget. To obtain bene cial short-term reversibility of physiological impairments, 4-week alcohol abstinence prior to surgery has been advised [21]. Several studies [20][21][22][23][24] also revealed that smoking was a risk factor for anastomotic leakage and increased the postoperative complications upon rectal surgery.…”

Section: Discussionmentioning

confidence: 99%

“…To obtain bene cial short-term reversibility of physiological impairments, 4-week alcohol abstinence prior to surgery has been advised [21]. Several studies [20][21][22][23][24] also revealed that smoking was a risk factor for anastomotic leakage and increased the postoperative complications upon rectal surgery. Although 40% of patients (4/10) with a history of smoking developed EJAL, this factor failed to reach statistical signi cance in the present study but should be further discussed in the future.…”

Section: Discussionmentioning

confidence: 99%

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Risk factors for esophagojejunal anastomotic leakage in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer: A retrospective cohort study

Jin

Liu

et al. 2020

Preprint

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Background: This study aimed to explore the risk factors associated with esophagojejunal anastomotic leakage (EJAL) in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer.Methods: 390 consecutive patients receiving Roux-en-Y esophagojejunostomy reconstruction after surgery were reviewed. Multivariate analysis was performed using a logistic regression model to identify independent risk factors for EJAL.Results: Of the 390 patients enrolled in this study, EJAL occurred in 10 patients (2.6%). One patient (1/10) with EJAL died. Univariate analysis identified age (P = 0.025), alcohol consumption (P = 0.019), pulmonary insufficiency (P = 0.049), and intraoperative blood loss (P = 0.015) as risk factors for EJAL. Of these four risk factors, age (P = 0.043) and alcohol consumption (P = 0.043) were retained as independent risk factors by multivariate analysis.Conclusions: Surgeons should be very careful about anastomotic leakage during the perioperative period, especially in patients with advanced age and a history of alcohol consumption. Pulmonary insufficiency and intraoperative blood loss, although not being identified as independent risk factors, should also be considered.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Risk factors for esophagojejunal anastomotic leakage in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer: A retrospective cohort study

Jin

Liu

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Although anastomotic leakage might be a complication driven by many factors, alcohol consumption has previously been associated with increased postoperative complications in colorectal cancer patients [20][21]. Rullier and Sorensen [22][23] reported that smoking and alcohol abuse were major risk factors for anastomotic leakage in colorectal surgery.…”

Section: Tumor-related Variablesmentioning

confidence: 99%

“…Moreover, a history of alcohol consumption is an influential factor in the development of postoperative complications that clinicians should not forget. To obtain beneficial short-term reversibility of physiological impairments, 4-week alcohol abstinence prior to surgery has been advised [21]. Several studies [20][21][22][23][24] also revealed that smoking was a risk factor for anastomotic leakage and increased the postoperative complications upon rectal surgery.…”

Section: Tumor-related Variablesmentioning

confidence: 99%

“…To obtain beneficial short-term reversibility of physiological impairments, 4-week alcohol abstinence prior to surgery has been advised [21]. Several studies [20][21][22][23][24] also revealed that smoking was a risk factor for anastomotic leakage and increased the postoperative complications upon rectal surgery. Although 40% of patients (4/10) with a history of smoking developed EJAL, this factor failed to reach statistical significance in the present study but should be further discussed in the future.…”

Section: Tumor-related Variablesmentioning

confidence: 99%

See 1 more Smart Citation

Risk factors for esophagojejunal anastomotic leakage in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer: A retrospective cohort study

Xing

Liu

et al. 2020

Preprint

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Background This study aimed to explore the risk factors associated with esophagojejunal anastomotic leakage (EJAL) in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer. Methods Consecutive patients receiving Roux-en-Y esophagojejunostomy reconstruction after surgery were reviewed. Multivariate analysis was performed using a logistic regression model to identify independent risk factors for EJAL. Results Of the 390 patients enrolled in this study, EJAL occurred in 10 patients (2.6%). One patient (1/10) with EJAL died. Univariate analysis identified age ( P = 0.025), alcohol consumption ( P = 0.019), pulmonary insufficiency ( P = 0.049), and intraoperative blood loss ( P = 0.015) as risk factors for EJAL. Of these four risk factors, age ( P = 0.043) and alcohol consumption ( P = 0.043) were retained as independent risk factors by multivariate analysis. Conclusions Surgeons should be very careful about anastomotic leakage during the perioperative period, especially in patients with advanced age and a history of alcohol consumption. Pulmonary insufficiency and intraoperative blood loss, although not being identified as independent risk factors, should also be considered.

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Association between alcohol use disorder and hospital outcomes in colectomy patients - A retrospective cohort study

Rolfzen

Mikulich‐Gilbertson

Natvig

et al. 2022

Journal of Clinical Anesthesia

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Impact of alcohol & smoking on the surgical management of gastrointestinal patients

Cited by 5 publications

References 108 publications

Risk factors for esophagojejunal anastomotic leakage in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer: A retrospective cohort study

Risk factors for esophagojejunal anastomotic leakage in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer: A retrospective cohort study

Risk factors for esophagojejunal anastomotic leakage in curative total gastrectomy combined with D2 lymph node dissection for gastric cancer: A retrospective cohort study

Association between alcohol use disorder and hospital outcomes in colectomy patients - A retrospective cohort study

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