Impact of Alcohol Consumption on Snoring and Sleep Apnea: A Systematic Review and Meta‐analysis

Burgos-Sanchez, Christian; Jones, Nolan; Avillion, Michael P.; Gibson, Steven J.; Patel, Jagatkumar A.; Neighbors, John; Zaghi, Soroush; Camacho, Macario

doi:10.1177/0194599820931087

Cited by 33 publications

(13 citation statements)

References 43 publications

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“…These were generally replicated in one study including healthy young adult (18-21 year-old) subjects, suggesting only minor differences between these subjects and other adult populations [147]. Heavy alcohol use is likely to negatively affect sleep, leading to reduced recovery [143]; in many cases, this may be a result of worsened snoring and obstructive sleep apnea [148].…”

Section: Alcoholmentioning

confidence: 77%

Troubleshooting a Nonresponder: Guidance for the Strength and Conditioning Coach

Gleason

Hornsby

Suarez

et al. 2021

Sports

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Ideally an athlete would continue to improve performance indefinitely over time, however improvement slows as the athlete approaches their genetic limits. Measuring performance is complex—performance may be temporarily depressed following aggressive training for multiple reasons, physiological and psychosocial. This reality may be vexing to the strength and conditioning coach, who, as a service provider, must answer to sport coaches about an athlete’s progress. Recently an evaluation mechanism for strength and conditioning coaches was proposed, in part to help coaches establish their effectiveness within the organization. Without formal guidance and realistic expectations, if an athlete is not bigger, leaner, stronger, etc. as a result of training within a specified timeframe, blame is often placed upon the strength and conditioning coach. The purpose of this article is to explore possible causes of what may be perceived as athlete non-responses to training and to provide guidance for the coach on how to handle those issues within their domain. A process of investigation is recommended, along with resources to assist coaches as they consider a broad range of issues, including enhancing existing testing methods, improving athlete behaviors, and adjusting processes designed to bring about performance improvement.

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Section: Alcoholmentioning

confidence: 77%

Troubleshooting a Nonresponder: Guidance for the Strength and Conditioning Coach

Gleason

Hornsby

Suarez

et al. 2021

Sports

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“…The number of clinical covariates available in this study was also somewhat limited. Thus, the potential impact of uncontrolled confounding behavioral and lifestyle factors (diet, exercise, alcohol, caffeine, tobacco use, and medications) 36 , 37 and treatment status to influence the current findings remain to be investigated. Like many digital health innovations and consumer-data research, there is a balance between data volume and the ability to capture all clinically relevant variables.…”

Section: Discussionmentioning

confidence: 99%

High night-to-night variability in sleep apnea severity is associated with uncontrolled hypertension

et al. 2023

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Obstructive sleep apnea (OSA) severity can vary markedly from night-to-night. However, the impact of night-to-night variability in OSA severity on key cardiovascular outcomes such as hypertension is unknown. Thus, the primary aim of this study is to determine the effects of night-to-night variability in OSA severity on hypertension likelihood. This study uses in-home monitoring of 15,526 adults with ~180 nights per participant with an under-mattress sleep sensor device, plus ~30 repeat blood pressure measures. OSA severity is defined from the mean estimated apnea–hypopnoea index (AHI) over the ~6-month recording period for each participant. Night-to-night variability in severity is determined from the standard deviation of the estimated AHI across recording nights. Uncontrolled hypertension is defined as mean systolic blood pressure ≥140 mmHg and/or mean diastolic blood pressure ≥90 mmHg. Regression analyses are performed adjusted for age, sex, and body mass index. A total of 12,287 participants (12% female) are included in the analyses. Participants in the highest night-to-night variability quartile within each OSA severity category, have a 50–70% increase in uncontrolled hypertension likelihood versus the lowest variability quartile, independent of OSA severity. This study demonstrates that high night-to-night variability in OSA severity is a predictor of uncontrolled hypertension, independent of OSA severity. These findings have important implications for the identification of which OSA patients are most at risk of cardiovascular harm.

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“…Alcohol induces sarcoplasmic reticulum Ca2+ mishandling, 21 and decreases atrial conduction velocity and atrial effective refractory period 22 leading to increased AF susceptibility. Additionally, alcohol consumption is associated with risks for AF such as elevation of blood pressure, 23 worsening of sleep apnea, 24 weight gain, 25 and left ventricular dysfunction. All of these effects of alcohol may in turn cause atrial structural and electrical remodeling, 26 leading to an increase in AF burden.…”

Section: Discussionmentioning

confidence: 99%

Alcohol Consumption Reduction and Clinical Outcomes of Catheter Ablation for Atrial Fibrillation

Takahashi

Nitta

Kobori³

et al. 2021

Circ: Arrhythmia and Electrophysiology

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Background - Abstinence from alcohol is effective for reduction of atrial fibrillation (AF) burden. However, effects of alcohol abstinence on clinical outcomes of catheter ablation for AF remain unknown. We sought to assess association of alcohol consumption reduction with clinical outcomes of catheter ablation for AF. Methods - In this multicenter prospective observational study, consecutive patients undergoing catheter ablation for AF were enrolled. All patients were requested to limit alcohol consumption to <20g per week after the ablation. The primary endpoint was AF/atrial tachycardia (AT) recurrence-free survival without antiarrhythmic drugs beyond a 3-month blanking period. Percent reduction of alcohol consumption from baseline to 1-year post-ablation, if freed from AF/AT for 1-year, or to AF/AT recurrence was assessed. Univariate and multivariate Cox regression analyses were performed to assess the association of the percent reduction of alcohol consumption with AF/AT recurrence-free survival as well as to determine the cutoff value for the percent reduction of alcohol consumption that yielded the largest difference in AF/AT recurrence-free survival. Results - Of 3474 patients enrolled in this study, analysis was performed in 1720 patients who consumed alcohol regularly before ablation (64&10 years, male 88%, paroxysmal AF 55.9%, persistent AF 31.6%, longstanding persistent AF 12.5%). Median baseline alcohol consumption was 140g per week (interquartile range [IQR]: 70-280g). Alcohol consumption during 1-year follow-up decreased to a median of 70g (IQR: 13-162g, p<0.0001). Multivariate Cox regression analysis demonstrated that alcohol reduction of ≥1% from baseline to 1-year follow-up (median reduction: 75%, [IQR: 45-100%]) was associated with lower risk of AF/AT recurrence (hazard ratio: 0.630, [95% confidence interval: 0.518-0.768], p <0.001), compared to alcohol reduction of <1% (median: 0%, [IQR: -20%-0%]). Conclusions - This study suggests that abstinence from alcohol improves clinical outcomes of catheter ablation for AF.

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Impact of Alcohol Consumption on Snoring and Sleep Apnea: A Systematic Review and Meta‐analysis

Cited by 33 publications

References 43 publications

Troubleshooting a Nonresponder: Guidance for the Strength and Conditioning Coach

Troubleshooting a Nonresponder: Guidance for the Strength and Conditioning Coach

High night-to-night variability in sleep apnea severity is associated with uncontrolled hypertension

Alcohol Consumption Reduction and Clinical Outcomes of Catheter Ablation for Atrial Fibrillation

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