An agroforestry practice produces different benefits, which enhance household incomes and diversification of products. This study was aimed to identifying existing agroforestry practices and to identify perception behind of agroforestry practice and to identify the opportunities and major constraints related to agroforestry practices in Fedis, Kersa and Jarso Districts of the lowland, midland and highlands agro ecologies, of East Hararghe Zone, oromia, Ethiopia. The study was based on a household survey conducted on 154 farm household heads; focus group discussions, key informant interviews and direct field observations were applied. The data were analyzed using analytical (SPSS 20.0) software packages to calculate descriptive statistics. Chi-squared tests were used to compare the agroforestry practices and agro ecologies. The result indicates that six AFPs exist in the study area namely; scattered trees on croplands (58%), hedge row intercropping (33%), home garden (22%), multipurpose trees on farmland (19%), live fence /boundary planting (18%), and wind breaks (4%) were dominant. Significant respondent number (51.96%) of practices is involved in agri-silvicultural system, most of the farmer's (45.12%) have positive attitude towards Agroforestry practices in the study area. Most of the respondents agreed on agro-forestry practices increased the construction input, soil fertility, food, and fodder. On the other hand, sacristy of land, moisture stress, diseases and pests, inadequate seedlings availability, and inadequate extension services are the major constraints. Results of the socio-economic characteristics respondents showed that gender, age, family size, and land holding positively and significantly influence the decision of the determined practice of household's and were significantly affected the choice of agroforestry practice by the households. Based on the survey, it is concluded that scattered trees on farmland, hedge row intercropping, and home garden AFP dominant practices across agro ecologies and were the most appropriate agro-forestry practices. This agro-forestry practices increased the construction input, soil fertility, food, and fodder in the area of land sacristy, moisture stress, diseases and pests. Therefore, further the tree integration efforts of farmers should be guided by scientific principles, the interaction tree species with annual crops and economic analysis of the individual agroforestry practices, domestication of nitrogen fixing trees, fruit tree species, and promoting sustainable agroforestry should be carried out.