Impact of ankylosing spondylitis on work in patients across the UK

Healey, Emma L.; Haywood, Kirstie L.; Jordan, Kelvin P.; Garratt, Andrew; Packham, Jon

doi:10.3109/03009742.2010.487838

Cited by 68 publications

(74 citation statements)

References 24 publications

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“…Presenteeism in AS patients has never been compared to the general population, but 53% of the patients (n 5 72) experienced limitations while at work and reported reduced efficiency due to AS (3.3 on a 0-10 scale) (2). The productivity loss at work in AS patients was estimated to be 8.3% (n 5 66) (7) and 18.9% (n 5 315) (8) using the 25-item and 16-item Work Limitations Questionnaires, respectively.…”

Section: Introductionmentioning

confidence: 99%

“…Several instruments have been developed, but they provide different results (2,7,8,17,(21)(22)(23)(24). Among the instruments for presenteeism assessment, a self-reported measure of productivity at work might be a relevant indicator for future adverse work outcomes, like sick leave, because it accounts not only for symptoms such as pain, stiffness, and fatigue, but also for the effects of these symptoms on working speed, concentration, and interpersonal interactions.…”

Section: Introductionmentioning

confidence: 99%

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Longitudinal Analyses of Presenteeism and Its Role as a Predictor of Sick Leave in Patients With Ankylosing Spondylitis

Tran‐Duy

Nguyen

Thijs

et al. 2015

Arthritis Care & Research

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Objective. To investigate, in a cohort of patients with ankylosing spondylitis (AS) adequately treated with infliximab, changes over time in presenteeism and the role of presenteeism relative to that of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI) in predicting sick leave. Methods. Data were analyzed from 71 patients with paid work and taking a stable dose of infliximab participating in a 96-week study with 5 assessment points. Covariates included presenteeism, sick leave, time, sex, age, BASDAI, BASFI, Bath Ankylosing Spondylitis Metrology Index, and part-or full-time work. Presenteeism represented the AS impact on productivity (by visual analog scale, range 0-10, where 10 5 completely unproductive). Sick leave represented the number of days absent from work due to AS in the last 6 months. A linear mixed-effects model for presenteeism, and hurdle and zero-inflated count models for sick leave were explored. Results. Mean 6 SD presenteeism ranged from 2.2 6 2.2 to 3.8 6 7.8, and sick leave occurred in 8-17% of the patients during the 6-month period. Presenteeism positively correlated with BASDAI and BASFI, but was not significantly influenced by time. The chance of incurring sick leave was affected by presenteeism but not by BASDAI and BASFI. Conditional on being absent from work, the effect of presenteeism on the length of sick leave (in days) was much stronger than BASDAI and BASFI. For presenteeism ‡5, an increase of 1 unit in presenteeism yielded an increase by 36-40% (or 2-12 days) in the length of sick leave during the following 6 months. Conclusion. Presenteeism, even measured by a simple visual analog scale, was an important factor to explain future sick leave.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Longitudinal Analyses of Presenteeism and Its Role as a Predictor of Sick Leave in Patients With Ankylosing Spondylitis

Tran‐Duy

Nguyen

Thijs

et al. 2015

Arthritis Care & Research

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“…В иссле-довании E.L. Healey и соавт. [5] при средней продолжи-тельности АС 17,3 года трудоустроенными остались лишь 60% больных.…”

Section: результатыunclassified

“…[4], доля нетрудоспособных больных АС уже через 12 мес от де-бюта болезни составляет 5%, доходя до 23% к 15-му году заболевания, а по данным E.L. Healey и соавт. [5] через 17 лет от начала болезни не могли работать 40% больных.…”

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Correlation Between Clinical Characteristics of Ankylosing Spondylitis and Work Capacity and Productivity

Подряднова¹,

Rm²,

Урумова³

et al. 2014

rsp

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Анкилозирующим спондилитом (АС) страдает 0,1-1,6% населения [1], причем пре-имущественно трудоспособного возраста. Развитие АС сопровождается нарастанием бо-ли, скованности и ограничения функции по-звоночника, что приводит к существенному снижению качества жизни (КЖ) [2], ранней инвалидизации и сокращению продолжи-тельности жизни пациентов. Возникают огра-ничения в профессиональной и повседневной О р и г и н а л ь н ы е и с с л е д о в а н и я The strongest correlation detected was that between WPAI aspects (R>0.5) and the intensity of pain assessed by visual analogue scale. BASFI index showed moderate correlation -with GRP (R=0.30) and close -with presenteeism and reduction in ADL (R=0.56 and R=0.71 respectively) and did not correlatewith absenteeism. Conclusion. AS activity was the main factor influencing work productivity. Presenteeism correlates with clinical characteristics of AS considerably stronger than absenteeism. All WPAI aspects correlated with the disease activity and degree of functional impairment.

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“…Анкилозирующий спондилоартрит (АС) отно-сится к тем ревматическим системным заболевани-ям, которые наносят огромный медико-социальный урон конкретному больному человеку и обществу в целом, а ощутимый экономический ущерб при этом испытывает любое государство [16,43]. Распростра-ненность АС среди населения в среднем составляет 0,1-0,3 % [7,35,46], преимущественно развивается в возрасте 20-35 лет, в 4 раза чаще у мужчин [21].…”

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Ювенильный Анкилозирующий Спондилит (Обзор Литературы И Собственные Данные)

Chernyshоva¹,

Polesovа²,

Yehudіna³

et al. 2021

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Представлены обзор современной литературы и данные собственных обследований 35 детей и 182 взрослых, страдающих анкилозирующим спондилитом. По сравнению с заболеванием у взрослых людей ювенильный анкилозирующий спондилит (ЮАС) имеет целый ряд особенностей клинического течения, который возникает исключительно у мальчиков, проявляется более частым поражением осевых суставов (плечевых, тазобедренных), развитием системного остеодефицита (остеопении, остеопороза), энтезитов (в частности, мыщелков бедренной кости и позвонковых сочленений, но не ахиллодинитов), увеита и кардиопатии, пролиферацией (а не деструкцией) участков кости в дебюте спондилопатии и редким вовлечением в процесс поясничного отдела позвоночника и формированием эпифизарного остеопороза, более высокими концентрациями в крови интерлейкинов-8 и -17, но меньшими значениями интерлейкина-1β, циркулирующих иммунных комплексов, фибриногена, иммуноглобулинов А и G. Возможно, будет целесообразным выделение ЮАС в отдельную нозологическую форму, как, например, ювенильного идиопатического артрита (в недавнем прошлом — ювенильного ревматоидного артрита).

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Impact of ankylosing spondylitis on work in patients across the UK

Cited by 68 publications

References 24 publications

Longitudinal Analyses of Presenteeism and Its Role as a Predictor of Sick Leave in Patients With Ankylosing Spondylitis

Longitudinal Analyses of Presenteeism and Its Role as a Predictor of Sick Leave in Patients With Ankylosing Spondylitis

Correlation Between Clinical Characteristics of Ankylosing Spondylitis and Work Capacity and Productivity

Ювенильный Анкилозирующий Спондилит (Обзор Литературы И Собственные Данные)

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