Impact of Antibacterial Activity of Physical Storage Extracts on Pathogenic Bacteria

Article history:IJMM 2019; 12(6): 409-418 Background and Aims: Marine Actinomycetes are gram-positive bacteria that sometimes are free, saprophytic or plant and animal-associated, including marine sponges. More than 75% of antibiotics and antimicrobial compounds are produced by actinomycetes. In recent years, due to the need for new drugs, marine microorganisms have been considered as new sources of potential production of significant metabolites. The purpose of this study is isolation and identification of marine sponge-associated Actinomycete and investigation of its antibacterial activity. Materials and Methods:The Actinomycete was isolated from the marine Sponge collected from the depths of coastal waters in Bushehr and screened for antibacterial activity on pathogenic microorganisms of Escherichia coli، Bacillus cereus، Klebsiella spp.، Salmonella spp. and Proteus spp. using a Disk Diffusion Method. For molecular identification, genomic DNA was first extracted from isolate and then, the16S rDNA gene was amplified by PCR and Sequenced. The results were analyzed using bioinformatic programs, Bioedit and MEGA6. Results:In this study, based on phylogeny studies, it was determined that the isolate belonged to thegenus Streptomyces, and biochemical studies showed that all tests except catalase and gram were negative; antibacterial activity study showed significant activity against three pathogenic bacteria, E. coli, Bacillus cereus and Salmonella spp. It was more active against Salmonella spp. (around 16mm inhibition zone diameter). Conclusions:The results showed that depths of the Bushehr coastal waters have marine sponge associated actinomycetes, which are a source of secondary metabolites with biological activity.

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Seaweed Bioactive Compounds against Pathogens and Microalgae: Potential Uses on Pharmacology and Harmful Algae Bloom Control

Zerrifi

Khalloufi

Oudra

et al. 2018

Marine Drugs

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Cyanobacteria are found globally due to their adaptation to various environments. The occurrence of cyanobacterial blooms is not a new phenomenon. The bloom-forming and toxin-producing species have been a persistent nuisance all over the world over the last decades. Evidence suggests that this trend might be attributed to a complex interplay of direct and indirect anthropogenic influences. To control cyanobacterial blooms, various strategies, including physical, chemical, and biological methods have been proposed. Nevertheless, the use of those strategies is usually not effective. The isolation of natural compounds from many aquatic and terrestrial plants and seaweeds has become an alternative approach for controlling harmful algae in aquatic systems. Seaweeds have received attention from scientists because of their bioactive compounds with antibacterial, antifungal, anti-microalgae, and antioxidant properties. The undesirable effects of cyanobacteria proliferations and potential control methods are here reviewed, focusing on the use of potent bioactive compounds, isolated from seaweeds, against microalgae and cyanobacteria growth.

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Impact of Antibacterial Activity of Physical Storage Extracts on Pathogenic Bacteria

Cited by 3 publications

References 26 publications

Green synthesis of silver nanoparticles using expired medicines and assessment of its antibacterial activity: A novel approach

Green synthesis of silver nanoparticles using expired medicines and assessment of its antibacterial activity: A novel approach

Isolation of ASR7 Actinomycete Isolated from S12 Demospongia Marine Sponge and Study of Its Antibacterial Activity

Seaweed Bioactive Compounds against Pathogens and Microalgae: Potential Uses on Pharmacology and Harmful Algae Bloom Control

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