Impact of atmospheric microparticles and heavy metals on external respiration function of urbanized territory population

Веремчук, Л. В.; Mineeva, Elena E.; Виткина, Т. И.; Gvozdenko, T. A.; Golokhvast, Kirill S.

doi:10.15275/rusomj.2017.0402

Cited by 12 publications

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“…It has been proven that the development and progression of a number of diseases, including asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, lung cancer, type 2 diabetes and obesity, may be associated with PM2.5 exposure. It has been previously demonstrated that the long-term PM2.5 exposure accelerates atherosclerosis and increases blood pressure [4,16,[30][31][32].…”

Section: Discussionmentioning

confidence: 99%

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Assessment of air pollution by small-sized suspended particulate matter in urbanized territories with various technogenic load (on the example of Vladivostok, Russia)

Barskova¹,

Виткина²,

Gvozdenko³

et al. 2019

Russ Open Med J

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The aim of the study was to estimate the pollution of the atmospheric surface layer by suspended particulate matter (SPM) in two districts of Vladivostok with different levels of technogenic load. Material and Methods -The air samples were taken in the "breathing zone" by an electric aspirator simultaneously to the liquid absorbing medium and on the filter, laser granulometry was used to assess the dispersion, and the mass concentration of the SPM fractions was calculated.Results -Ultrafine particles were detected in the air in the area with a high man-made load. Air levels of particles with an aerodynamic diameter of 0.1-1 μm, 1-2.5 μm (respirable fraction) and 2.5-10 μm (tracheobronchial fraction) were 5, 2.7 and 3.3 times higher, respectively, in the area with a high man-made load in comparison with the area with insignificant technogenic load. Conclusion -Particles with an aerodynamic diameter less than 10 μm, which have the most pathogenic effect, prevail in the air in the urbanized area with a high technogenic load. The predominance of SPM fractions with an aerodynamic diameter more than 10 μm is a characteristic feature of air pollution in the territory with a low man-made load.

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Section: Discussionmentioning

confidence: 99%

“…The adverse effect of SPM on the human body mainly depends on their sizes and concentration in the air [4][5][6]. The SPM classification for hygienic assessment of dispersity and health effects is based on the ability of particles with a certain range of aerodynamic diameter to penetrate various parts of the human respiratory tract.…”

Section: Introductionmentioning

confidence: 99%

Assessment of air pollution by small-sized suspended particulate matter in urbanized territories with various technogenic load (on the example of Vladivostok, Russia)

Barskova¹,

Виткина²,

Gvozdenko³

et al. 2019

Russ Open Med J

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“…Sampling of SPMs was carried out in the continental (138 samples) and island parts (132 samples) of Vladivostok during the hours of intense technogenic air pollution (10 a.m.-1 p.m.) in the period of 2013-2018 [17] (Figure 1). moving micro-sized SPMs from the body leads to their accumulation, which may tribute to the development of bronchopulmonary diseases [13][14][15]. Oxidative stres systemic inflammatory response play an important role in the pathogenesis of chopulmonary diseases [16].…”

Section: Methodsmentioning

confidence: 99%

“…The incorporation of UFPs leads to the disruption of functioning and energy state of cells [12]. The impossibility of quickly removing micro-sized SPMs from the body leads to their accumulation, which may contribute to the development of bronchopulmonary diseases [13][14][15]. Oxidative stress and systemic inflammatory response play an important role Atmosphere 2021, 12, 1010 2 of 10 in the pathogenesis of bronchopulmonary diseases [16].…”

Section: Introductionmentioning

confidence: 99%

Estimation of the Size Distribution of Suspended Particulate Matters in the Urban Atmospheric Surface Layer and Its Influence on Bronchopulmonary Pathology

et al. 2021

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The surface layer of the urban atmosphere significantly affects human health. Its quality depends on the level of air pollution. The aim was to determine the size distribution of suspended particulate matters (SPMs) in the atmospheric surface layer of Vladivostok city and to assess the response of the blood immune and metabolic parameters of the population with bronchopulmonary pathology. Sampling of SPMs was conducted in the continental zone of the city with a high level of technogenic pollution (138 samples) and the island part of the city with an insignificant level of technogenic pollution (132 samples). The SPM fractional composition was analyzed by laser granulometry. We examined patients with bronchopulmonary pathology living in a one-kilometer zone centered on sampling area for at least 5 years (continental territory—220 patients, island territory—176 patients). We calculated the D% index characterizing the integral response of the blood immune and metabolic parameters to the exposure of dust fractions. It was found that PM > 10 (mainly of a natural origin) predominate in the island zone with insignificant level of technogenic pollution. The PM10 fraction prevails in the area with a high level of technogenic pollution. The response of the immune and metabolic systems to the exposure to microparticles in population living in the marine and forest/park zone of the island indicates a health-improving effect of the area. Low values of D% were detected for the patients living in the area with a high air pollution level, indicating a pathogenic reaction of immune and prooxidant-oxidative systems.

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“…Особенно уязвимой к воздействию пылевых фракций является когорта лиц с респираторной патологией [17,18]. Невозможность быстрого выведения микроразмерных ТВЧ из организма приводит к их накоплению, что может способствовать развитию и прогрессированию бронхолегочной патологии [5,19,20]. Согласно полученным результатам, наибольшее патогенное воздействие пылевые фракции оказывают на лиц с ХОБЛ (D ин %=0,81) и БА (D ин %=0,67).…”

Section: обсуждение результатов исследованияunclassified

Impact of air dust fractions on the immune system in patients with bronchopulmonary pathology

Kondratyeva

Веремчук

Виткина

2023

Bûlletenʹ fiziologii i patologii dyhaniâ

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Introduction. The study of disorders that develop in the immune system under the influence of technogenic factors remains a very urgent problem. Aim. To identify criteria for the impact of trigger dust fractions of the atmospheric air in Vladivostok (in the ranges: 0-1, 1-10, 10-50, 50-100, 100-400, 400-700, >700 microns) on the human immune system with respiratory diseases. Materials and methods. The objects of the study were the fractional composition of suspended particulate matter (SPM) in the air of Vladivostok and the immune system of residents with bronchopulmonary pathology. The study included 320 people: patients with asthma − 112, chronic obstructive pulmonary disease (COPD) of a stable course − 107, healthy people − 101. Using the multiple correlation, the indicators characterizing the integral response of the immune system parameters to the impact of SPM were determined. Results. The results obtained for the groups of subjects showed a difference in the number of factors of influence and immune responses to their influence. Dust fractions of the air form the greatest pathogenic effect in individuals with COPD. There is a negative reaction to all the studied dust fractions, however, the reaction of the immune system is maximum in the range from 0 to 100 microns (Nr =13, Dp %=0.13-0.19%). For the individuals with asthma, the maximum pathogenic effect is exerted by nanofractions of 0-1 μm (Nr =4, Dp =0.2%). Conclusion. Dust fractions negatively affect the immune system of all studied cohorts of the population of Vladivostok. However, in the individuals with respiratory diseases, dust air pollution causes a more pronounced response of the immune system.

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Impact of atmospheric microparticles and heavy metals on external respiration function of urbanized territory population

Cited by 12 publications

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Assessment of air pollution by small-sized suspended particulate matter in urbanized territories with various technogenic load (on the example of Vladivostok, Russia)

Assessment of air pollution by small-sized suspended particulate matter in urbanized territories with various technogenic load (on the example of Vladivostok, Russia)

Estimation of the Size Distribution of Suspended Particulate Matters in the Urban Atmospheric Surface Layer and Its Influence on Bronchopulmonary Pathology

Impact of air dust fractions on the immune system in patients with bronchopulmonary pathology

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