Impact of Atrial Fibrillation on Quality of Life

Vintila, A.; Stanciu, Adina Elena; Horumba, M.; Vintila, V.; Lupușoru, Mircea Denis; Gurghean, A.

doi:10.1097/01.hjh.0000572360.09405.f4

Cited by 4 publications

(3 citation statements)

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“…The bespoke questionnaire (see online supplemental file 1 ) assessed comorbidities, daily exercise, medication for AF and the impact of COVID-19 on the patient’s healthcare usage. The AF-specific questionnaire was the Atrial Fibrillation Effect on QualiTy of Life (AFEQT), 10 which assesses AF in three domains: AF symptoms, the effect of AF on activities and concerns about AF treatment. The second was the EuroQol 5D (EQ5D-5L) 11 questionnaire, which is a generic QoL instrument often used to derive health utilities and thereby assess the cost-effectiveness of healthcare interventions.…”

Section: Methodsmentioning

confidence: 99%

Impact of COVID-19 on patients awaiting ablation for atrial fibrillation

et al. 2022

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ObjectiveAtrial fibrillation (AF) ablation services were significantly affected by the COVID-19 pandemic. We aimed to evaluate a symptom-based clinician prioritisation scheme for waiting list management compared with patient-completed quality of life (QoL) scores. We also sought to understand factors influencing QoL, particularly the impact of COVID-19, on patients awaiting AF ablation, via a bespoke questionnaire.MethodsPatients awaiting AF ablation were sent two QoL questionnaires (Atrial Fibrillation Effect on QualiTy of Life (AFEQT) and EuroQol 5D (EQ5D-5L)) and the bespoke questionnaire. At a separate time point, patients were categorised as C1—urgent, C2—priority or C3—routine by their cardiologist based on review of clinic letters.ResultsThere were 118 patients included with priority categorisation available for 86 patients. Median AFEQT scores were lower in C2 (30.4; 17.2–51.9) vs C3 patients (56.5; 32.1–74.1; p<0.01). Unplanned admission occurred in 3 patients in C3 with AFEQT scores of <40. Although 65 patients had AF symptoms during the pandemic, 43.1% did not seek help where they ordinarily would have. An exercise frequency of ≥3–4 times a week was associated with higher AFEQT (56.5; 41.2–74.1; p<0.001) and EQ5D (0.84; 0.74–0.88; p<0.0001) scores.ConclusionThe QoL of patients awaiting AF ablation is impaired and AFEQT helps to identify patients at risk of admission, over and above physician assessment. COVID-19 influenced patients seeking medical attention with symptomatic AF when they normally would. Regular exercise is associated with better QoL in patients awaiting AF ablation.

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Section: Methodsmentioning

confidence: 99%

Impact of COVID-19 on patients awaiting ablation for atrial fibrillation

et al. 2022

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“…The fact that POAF may lead to chronic AF then of course introduces all adverse events associated with chronic AF into the POAF arena. Patients with chronic AF show a dramatic increase in the incidence of pathologies such as stroke and heart failure (Chen et al 2018, Vintila et al 2019). Based on the economic, health and social impact from atrial fibrillation, these results are certainly alarming and accentuate the harmful potential of POAF (Chen et al 2018, Vintila et al 2019.…”

Section: Long-standing Atrial Fibrillation As a Consequence Of Poafmentioning

confidence: 99%

“…Patients with chronic AF show a dramatic increase in the incidence of pathologies such as stroke and heart failure (Chen et al 2018, Vintila et al 2019). Based on the economic, health and social impact from atrial fibrillation, these results are certainly alarming and accentuate the harmful potential of POAF (Chen et al 2018, Vintila et al 2019. Therefore, it is clear that POAF is a clinical entity that deserves attention and probably the investment of efforts to combat it through new medical therapies, new surgical approaches and new therapeutic alternatives.…”

Section: Long-standing Atrial Fibrillation As a Consequence Of Poafmentioning

confidence: 99%

Atrial fibrillation after cardiac surgery: A systematic review and meta-analysis

Caldonazo

Kirov

Rahouma

et al. 2023

The Journal of Thoracic and Cardiovascular Surgery

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Objective: New-onset post-operative atrial fibrillation (POAF) after cardiac surgery is common, with rates up to 60%. POAF has been associated with early and late stroke, but its association with other cardiovascular outcomes is less known. The objective was to perform a meta-analysis of the studies reporting the association of POAF with perioperative and long-term outcomes in cardiac surgery. M ethod s: We performed a systematic review and a meta-analysis of studies presenting outcomes for cardiac surgery based on the presence or absence of POAF. MEDLINE, EMBASE and Cochrane Library were assessed, 57 studies (246,340 patients) were selected. Peri-operative mortality was the primary outcome. Inverse variance method and random model were performed. Leave-one-out analysis, sub-group analyses and meta-regression were conducted. Results: POAF was associated with peri-operative mortality (odds ratio [OR]= 1.92, 95% confidence interval [CI] 1.58; 2.33), peri-operative stroke (OR= 2.17, 95% CI 1.90; 2.49), peri-operative myocardial infarction (OR= 1.28, 95% CI 1.06; 1.54), perioperative acute renal failure (OR= 2.74, 95% CI 2.42; 3.11), hospital (standardized mean difference [SMD]= 0.80, 95% CI 0.53; 1.07) and ICU stay (SMD= 0.55, 95% CI 0.24; 0.86), long-term mortality (incidence rate ratio [IRR]= 1.54, 95% CI 1.40; 1.69), long-term stroke (IRR= 1.33, 95% CI 1,21;1,46) and long-standing persistent atrial fibrillation (IRR= 4.73, 95% CI 3.36; 6.66). Con clusion :The results suggest that POAF in cardiac surgery is associated with an increased occurrence of most short and long-term cardiovascular adverse events. However, the causality of this association remains to be established.

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