Impact of beta-blockers on mortality and cardiovascular disease outcomes in patients with obstructive sleep apnoea: a population-based cohort study in target trial emulation framework

Electrochemical screening of selected β-blockers at a polarized liquid–liquid interface

“…4. The black data points (circles) represent experimentally extracted values whereas the red dashed line is the best fit calculated using eqn (6).…”

“…The concentrations of the studied chemical species with zero net charge in the aqueous and organic phases are denoted as c aq c and c org c , respectively. In eqn (6), K D serves as the adjustable variable, enabling the optimal fitting to the experimental data represented by the solid red line (refer to Fig. 4).…”

“…Insights into β-blocker side effect profiles are crucial for clinicians to optimize their therapeutic applications and adapt treatment strategies to individual patient requirements. 6,7 In addition to their adrenergic receptor-blocking effects, β-blockers have the ability to increase cardiac relaxation and exert calming neurological effects, thus reducing anxiety and stabilizing motor efficiency. Due to these effects, β-blockers are listed by the World Anti-Doping Agency (WADA) as prohibited substances.…”