The chapter provides an overview of the advances made in the field of structural integrity and failure with a specific focus on reinforced concrete structures. It begins with a brief history of reinforced concrete and covers its structural properties and characteristics. It then delves into the mechanics of reinforced concrete structures, including the various forces that act on them, and the design and construction of these structures. It delves into the basic mechanics, stressing the concrete’s performance under loading and its inherent material properties. The focus then shifts to the design principles applied to reinforced concrete structures, and the consideration of critical structural elements like beams, slabs, columns, and foundations. Various advances in reinforced concrete technology, including High-Performance Concrete, Fiber-Reinforced Concrete, Self-Compacting Concrete, and the use of nanomaterials, are explored. The chapter provides insights into methods for the analysis and assessment of reinforced concrete structures, discussing non-destructive testing methods, structural health monitoring, and finite element analysis. It examines the causes of failure, including material quality, overloading, design flaws, environmental factors, and construction errors. Several case studies of notable building failures are highlighted, emphasizing lessons learned and the importance of safe construction practices. The chapter concludes by looking at future directions in reinforced concrete, encompassing advanced materials, digital technology, sustainable construction practices, and resilience-based design.