Impact of BMI Variations on Survival in Elderly Hemodialysis Patients

Villain, Cédric; Écochard, René; Genet, Leslie; Jean, G.; Kuentz, François; Lataillade, Dominique; Legrand, E; Moreau-Gaudry, Xavier; Fouque, Denis

doi:10.1053/j.jrn.2015.05.004

Cited by 19 publications

(14 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, intentional weight loss may differ from unintentional wasting in these populations. In older age groups, hemodialysis patients with stable weight had a longer survival than elderly who lose or gain weight [30]. Death rates of obese younger dialysis patients (< 65 years) are 1.7-fold higher than for the older group (> 65 years) after adjustment for comorbidity and treatment modality [31].…”

Section: Obesity In Advanced Ckd and Dialysis: A Paradoxmentioning

confidence: 97%

Preventive Nephrology: The Role of Obesity in Different Stages of Chronic Kidney Disease

Pommer¹

2018

Kidney Dis

View full text Add to dashboard Cite

Background: Obesity is increasing worldwide and has become a nontraditional risk factor in chronic kidney disease (CKD). Summary: Obesity-related nephropathy may aggravate renal complications of the metabolic syndrome and progress to advanced CKD stages, while obesity in early stages of CKD is clearly related to the development of kidney disease. A high body mass index (BMI) in advanced CKD stages and dialysis is an advantage for survival (so called “obesity paradox”). A high lean body to fat mass index indicates a beneficial state of body composition. In contrast, loss of muscle mass with increasing fat mass causes “sarcopenia obesity,” which is related to unfavorable outcomes in renal replacement therapy. Obesity (BMI > 30–35) in renal transplant recipients is associated with a higher risk of complications such as delayed graft function, increased rates of rejection, and graft loss. While conservative management of morbid obesity is failing in most cases, bariatric surgery seems to be an option in some cases to improve renal complications in the early stage of CKD or in transplant candidates. Key Message: In conclusion, obesity is increasingly prevalent among CKD patients. Adequate management with respect to the specific role of obesity in different stages of CKD should be integrated in routine renal care.

show abstract

Section: Obesity In Advanced Ckd and Dialysis: A Paradoxmentioning

confidence: 97%

Preventive Nephrology: The Role of Obesity in Different Stages of Chronic Kidney Disease

Pommer¹

2018

Kidney Dis

View full text Add to dashboard Cite

show abstract

“…However, elderly hemodialysis patients still had a three-to six-fold higher mortality risk than nonelderly hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS) study [2]. There are many identi ed factors contributing to the increased mortality risk in these patients, such as blood pressure, urine albumin, anemia, and serum creatinine [3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

The Association Between the Serum Uric Acid to Creatinine Ratio and All-Cause Mortality in Elderly Hemodialysis Patients

Ding¹,

Yao

Chun-lei³

et al. 2022

Preprint

View full text Add to dashboard Cite

Purpose: The present study investigated the association between the serum uric acid to creatinine ratio (SUA/Scr) and all-cause mortality among elderly hemodialysis patients.Methods: A total of 222 patients (≥ 60 years) who received hemodialysis more than 8 hours per week at Tai Zhou No. 2 People’s Hospital for at least 3 months were enrolled in the present study from January 2015 to December 2019. Clinical characteristics were obtained from the hemodialysis database, and survival information was recorded during the follow-up period. Multiple Cox regression was carried out to analyze the association between SUA/Scr and all-cause mortality. The survival rate of each group was calculated by the Kaplan-Meier method, and the ratio of survival curves was analyzed by the log-rank test.Results: During the 19-month observation period, 78 patients died. Individuals in the nonsurviving group had significantly older ages (P<0.001), body mass index (BMI) (P=0.004), serum creatinine (P=0.005) and prealbumin (P=0.006) than surviving patients. After adjusting for age, sex, BMI, prealbumin and serum creatinine, a higher ratio of SUA/Scr was independently associated with a higher risk of all-cause mortality (HR: 1.375; 95% CI: 1.023-1.848; P=0.035).Conclusion: The serum uric acid to creatinine ratio is strongly associated with all-cause mortality in elderly hemodialysis patients.

show abstract

“…Body mass index (BMI) and BMI percentage change per year are associated with survival in elderly adults undergoing hemodialysis. 2 These two covariates were therefore used in the models to assess the effect of SAlb on survival independent of BMI.…”

Section: Methodsmentioning

confidence: 99%

Prognostic Value of Serum Albumin Changes Over Time in Elderly Adults Undergoing Hemodialysis

Villain

Fouque

Genet

et al. 2016

J American Geriatrics Society

Self Cite

View full text Add to dashboard Cite

Impact of BMI Variations on Survival in Elderly Hemodialysis Patients

Cited by 19 publications

References 32 publications

Preventive Nephrology: The Role of Obesity in Different Stages of Chronic Kidney Disease

Preventive Nephrology: The Role of Obesity in Different Stages of Chronic Kidney Disease

The Association Between the Serum Uric Acid to Creatinine Ratio and All-Cause Mortality in Elderly Hemodialysis Patients

Prognostic Value of Serum Albumin Changes Over Time in Elderly Adults Undergoing Hemodialysis

Contact Info

Product

Resources

About