Impact of Breast Cancer Awareness Month on Public Interest in the United States between 2012 and 2021: A Google Trends Analysis

Nishimura, Yoshito; Acoba, Jared D.

doi:10.3390/cancers14102534

Cited by 21 publications

(23 citation statements)

References 28 publications

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“…A prior systematic review demonstrated the efficacy of social media as a means of disseminating information, such as educational materials regarding cancer screening, though the evidence was notably limited [ 24 ]. Another study examined the impact of BCAM on public awareness of breast cancer in the United States, showing similar results to the present study with suggestions to employ online marketing and social media approaches during BCAM [ 25 ]. Online campaigns may also increase accessibility to preventive information related to breast cancer, especially in countries outside of the United States.…”

Section: Discussionsupporting

confidence: 82%

Google Trends in Breast and Cervical Cancer Searches From 2008 to 2021: An Infodemiology Study

Bhagavathula¹,

Bansil²,

Nishimura³

2023

Cureus

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Introduction: Breast and cervical cancer are the leading causes of cancer death among women worldwide. Given the growing concern, cervical cancer awareness month (CCAM) in January and Breast cancer awareness month (BCAM) in October occur annually as global health observances to raise public awareness. This infodemiology study aimed to assess trends in public online searches for breast cancer and cervical cancer following the annual BCAM and CCAM from 2008 to 2021. Methods: Google Trends (GT) was used to investigate online searches for "breast cancer" and "cervical cancer" from January 1, 2008, to December 31, 2021. (168 months). A joinpoint regression analysis was used to identify statistically significant weekly percentage changes (WPCs) and monthly percentage changes (MPCs) trends over time. Results: Breast cancer searches increased in October (BCAM) every year, while cervical cancer searches increased in January (CCAM) in 2013, 2019, and 2020. Joinpoint regression analysis revealed a significant negative trend in "breast cancer" searches from 2008 to 2021 (MPC: -0.2%, 95% CI: -0.3 to -0.1) and an upward trend in "cervical cancer" searches from May 2017 to December 2021 (MPC: 0.5%, 95% CI: 0.2 to 0.7). Conclusion: Online searches on "breast cancer" remain consistently high only during BCAM, and "cervical cancer" has increased by 0.5% MPC since May 2017. Our findings can inform online interventions like event-based opportunities (BCAM and CCAM) and Google Ads to raise public awareness of breast and cervical cancer.

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Section: Discussionsupporting

confidence: 82%

Google Trends in Breast and Cervical Cancer Searches From 2008 to 2021: An Infodemiology Study

Bhagavathula¹,

Bansil²,

Nishimura³

2023

Cureus

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“…Cancer is one of the leading causes of death worldwide, accounting for an estimated 10 million deaths in 2020 ( Ferlay et al, 2021 ). In the same period, there were approximately 19.5 million new cancer cases and 685,000 deaths with female breast cancer being the most diagnosed cancer (2.26 million cases) ( Ferlay et al, 2021 ; Nishimura and Acoba, 2022 ). Chemotherapy is among the extensively utilized treatment methods in the fight against breast cancer ( Shahidian et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Cytotoxic mixed-ligand complexes of Cu(II): A combined experimental and computational study

et al. 2022

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Herein, we report the synthesis of mixed-ligand Cu(II) complexes of metformin and ciprofloxacin drugs together with 1,10-phenanthroline as a co-ligand. The synthesized complexes were characterized using different spectroscopic and spectrometric techniques. In vitro cytotoxic activity against human breast adenocarcinoma cancer cell line (MCF-7) as well as antibacterial activity against two gram-negative and two gram-positive bacterial strains were also investigated. The analyses of the experimental results were supported using quantum chemical calculations and molecular docking studies against estrogen receptor alpha (ERα; PDB: 5GS4). The cytotoxicity of the [Cu(II) (metformin) (1,10-phenanthroline)] complex (1), with IC50 of 4.29 µM, and the [Cu(II) (ciprofloxacin) (1,10-phenanthroline)] complex (2), with IC50 of 7.58 µM, were found to be more effective than the referenced drug, cisplatin which has IC50 of 18.62 µM against MCF-7 cell line. The molecular docking analysis is also in good agreement with the experimental results, with binding affinities of –7.35, –8.76 and –6.32 kcal/mol, respectively, for complexes 1, 2 and cisplatin against ERα. Moreover, complex 2 showed significant antibacterial activity against E. coli (inhibition diameter zone, IDZ, = 17.3 mm), P. aeruginosa (IDZ = 17.08 mm), and S. pyogen (IDZ = 17.33 mm), at 25 μg/ml compared to ciprofloxacin (IDZ = 20.0, 20.3, and 21.3 mm), respectively. Our BOILED-egg model indicated that the synthesized metal complexes have potentially minimal neurotoxicity than that of cisplatin.

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“…We preferred Google Trends because it is a free, open-source tool previously used in numerous assessments to analyse search term volumes entered in the Google search engine. 7 , 8 , 14 , 15 Also, other search engines constitute < 10% of the total search market share, and many don’t have publicly accessible data analytical tools. 16 RSV indicates the popularity of a keyword and is calculated by dividing the sampled search data points by the total number of searches done in the specific region and time, after which the resulting value is scaled from 0 to 100.…”

Section: Methodsmentioning

confidence: 99%

Increasing trends in online information-seeking and decreasing trends of funded research for polycystic ovary syndrome: An 18-year joinpoint analysis of Google Trends data from 2004 to 2022

Malhotra,

Kempegowda

2023

DIGITAL HEALTH

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Background The internet has become the primary source of health-related information, and online health information-seeking behaviour has been used as a reliable surrogate of public awareness. We studied the trends of search interest in polycystic ovary syndrome over time and whether funding for polycystic ovary syndrome research corresponded with the changes in search interest. We also studied the geographic reach of polycystic ovary syndrome interest and whether polycystic ovary syndrome awareness month is an effective strategy to increase polycystic ovary syndrome interest. Methods We performed joinpoint regression on relative search volume data for polycystic ovary syndrome using Google Trends from 2004 to 2022, comparing weekly, monthly and yearly trends. We retrieved the total polycystic ovary syndrome-related articles from 1980 to 2022 to study funded and unfunded literature trends. We did a Mann-Whitney U-test analysis comparing the mean relative search volume during the polycystic ovary syndrome awareness month versus the rest of the weeks yearly. Results Three joinpoints were seen at months 70, 196, and 199 months which were statistically significant when compared to the null hypothesis of zero joinpoints ( p = .0002), one joinpoint ( p = .0002), and two joinpoints ( p = .0395), respectively. The search interest of ‘Polycystic ovary syndrome’ was seen in 195 regions globally. The mean relative search volume in September corresponding to polycystic ovary syndrome awareness month was higher than other months from 2013 to 2022. Of the 41,292 journal articles analysed, there was a positive trend in funded polycystic ovary syndrome research from the 2000s until the onset of the COVID-19 pandemic. Conclusions An increasing polycystic ovary syndrome search interest is probably driven by major legislative and scientific events suggesting the importance of such events. Polycystic ovary syndrome Awareness Month is an effective international awareness initiative to increase online polycystic ovary syndrome information-seeking behaviour. The declining trend in funding is a concern as it mismatches with the continued increase in information-seeking behaviour globally.

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Impact of Breast Cancer Awareness Month on Public Interest in the United States between 2012 and 2021: A Google Trends Analysis

Cited by 21 publications

References 28 publications

Google Trends in Breast and Cervical Cancer Searches From 2008 to 2021: An Infodemiology Study

Google Trends in Breast and Cervical Cancer Searches From 2008 to 2021: An Infodemiology Study

Cytotoxic mixed-ligand complexes of Cu(II): A combined experimental and computational study

Increasing trends in online information-seeking and decreasing trends of funded research for polycystic ovary syndrome: An 18-year joinpoint analysis of Google Trends data from 2004 to 2022

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