Impact of cardiovascular comorbidities on inpatient mortality in patients hospitalized with neutropenic fever

Atallah‐Yunes, Suheil Albert; Kadado, Anis John; Haddadin, Faris; Sawalha, Khalid; Hernández-Montfort, Jaime; Ali, Syed Sohail

doi:10.1007/s00520-020-05518-6

Support Care Cancer

2020

DOI: 10.1007/s00520-020-05518-6

|View full text |Cite

Impact of cardiovascular comorbidities on inpatient mortality in patients hospitalized with neutropenic fever

Suheil Albert Atallah‐Yunes

Anis John Kadado

Faris Haddadin

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

2023

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ebrile neutropenia is a serious complication in patients receiving chemotherapy and is one of the most common causes of hospitalization in this population. 1 This condition is considered an oncologic emergency, and if not addressed in a timely manner, it may progress to multiorgan system failure and may be fatal. Studies have shown that among patients who have neutropenic fever treated with empirical antibiotics, mortality rates range from 4% to 20%; among those who aren't treated with antibiotics, the mortality rate can be as high as 70%.…”

mentioning

confidence: 99%

See 1 more Smart Citation

CE: Febrile Neutropenia in the Chemotherapy Patient

Foley

Hoffman

2023

AJN, American Journal of Nursing

View full text Add to dashboard Cite

Febrile neutropenia is a serious complication of chemotherapy treatment and may present as the only clinical sign of infection. If not addressed in a timely manner, it may progress to multisystem organ failure and may be fatal. Initial assessment of fever in those receiving chemotherapy requires prompt administration of antibiotics, ideally within one hour of presentation. Depending on the clinical status of the patient, antibiotic treatment may occur in the inpatient or outpatient setting. Nurses play an important role in the identification and treatment of patients at high risk for febrile neutropenia through assessment and adherence to clinical practice guidelines. In addition, nurses play an active role in patient education regarding risk factors, protective measures, and signs and symptoms of infection in the immunocompromised oncology patient.

show abstract

mentioning

confidence: 99%

“…Febrile neutropenia is a serious complication in patients receiving chemotherapy and is one of the most common causes of hospitalization in this population 1. This condition is considered an oncologic emergency, and if not addressed in a timely manner, it may progress to multiorgan system failure and may be fatal.…”

mentioning

confidence: 99%

CE: Febrile Neutropenia in the Chemotherapy Patient

Foley

Hoffman

2023

AJN, American Journal of Nursing

View full text Add to dashboard Cite

show abstract

Delay in Time to Antibiotics for De Novo Inpatient Neutropenic Fever May Not Impact Overall Survival for Patients With a Cancer Diagnosis

Villars

Gardner

Binder

2022

American Journal of Medical Quality

View full text Add to dashboard Cite

Neutropenic fever (NF) is an oncologic emergency for which expert consensus recommends that anti-pseudomonas antibiotics be administered within 60 minutes of detection. This study investigated whether delays in time to antibiotics (TTA) impacted overall survival (OS) for patients with hematological malignancies who developed inpatient NF via a retrospective cohort study of 187 de novo NF cases categorized by TTA (<1, 1–2, 2–3, 3–4 and >4 hours). OS at 180 days post-NF episode was compared using Kaplan-Meier estimates and multivariable Cox proportional hazards model. TTA did not significantly affect OS (P = 0.420). Patients with Charleston Comorbidity Indexes ≥3, a measure of overall health, had higher hazard (hazard ratio [HR] = 2.728, 95% confidence interval, 1.265-5.882, P = 0.010). TTA delays in the hospital may not be long enough to cause significant patient harm. Larger studies may be needed to detect small, but significant mortality differences.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Impact of cardiovascular comorbidities on inpatient mortality in patients hospitalized with neutropenic fever

Cited by 2 publications

References 20 publications

CE: Febrile Neutropenia in the Chemotherapy Patient

CE: Febrile Neutropenia in the Chemotherapy Patient

Delay in Time to Antibiotics for De Novo Inpatient Neutropenic Fever May Not Impact Overall Survival for Patients With a Cancer Diagnosis

Contact Info

Product

Resources

About