Impact of childhood trauma and affective temperament on resilience in bipolar disorder

Ünübol, Başak; Kesebir, Sermin

doi:10.1016/s0924-977x(17)31506-7

European Neuropsychopharmacology

2017

DOI: 10.1016/s0924-977x(17)31506-7

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Impact of childhood trauma and affective temperament on resilience in bipolar disorder

Başak Ünübol¹,

Sermin Kesebir²

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2022

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Childhood Trauma and Sleep-related Daytime Dysfunction in Patients with Bipolar II Disorder

Chen

Hsieh

et al. 2022

Taiwanese Journal of Psychiatry

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Background: Sleep quality is an important predictor for prognosis of bipolar disorder (BD). Factors associated with sleep quality in BD such as childhood trauma experience merit investigation. Methods: We used the Pittsburgh Sleep Quality Index (PSQI), Childhood Trauma Questionnaire (CTQ), and Measurement of Support Functions (MSF) to access patients with BD-I (n = 31), and those with BD-II (n = 34). Results: We found that 71.4% of patients with BD-I and 90.9% of those with BD-II had poor sleep quality. Significantly higher CTQ physical abuse score and poor life quality were found among patients with BD-II (b = −0.008, Wald χ 2 (1) = 5.024, p < 0.05). This effect remained robust (b = −0.012, Wald χ 2 (1) = 8.150, p < 0.01) after controlling the use of drug (sedative, benzodiazepine, antipsychotic, and antidepressant). Moreover, the experience of childhood trauma was associated with poor sleep quality among patients with BD-II. A buffer effect of social support between physical abuse and daytime dysfunction, as measured by PSQI, was found in patients with BD-II, but not in those with BD-I. Conclusion: Social adversity and support were associated with sleep quality in patients with BD-II. This finding implied a stress-buffering model in patients with BD-II. But the underlying biological mechanism remains unclear.

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Childhood Trauma and Sleep-related Daytime Dysfunction in Patients with Bipolar II Disorder

Chen

Hsieh

et al. 2022

Taiwanese Journal of Psychiatry

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Impact of childhood trauma and affective temperament on resilience in bipolar disorder

Cited by 1 publication

References 25 publications

Childhood Trauma and Sleep-related Daytime Dysfunction in Patients with Bipolar II Disorder

Childhood Trauma and Sleep-related Daytime Dysfunction in Patients with Bipolar II Disorder

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