Impact of climate and air pollution on acute coronary syndromes: an update from the European Society of Cardiology Congress 2017

Kałużna‐Oleksy, Marta; Aunan, Kristin; Rao, Shilpa; Kjellström, Tord; Agewall, Stefan; Atar, Dan

doi:10.1080/14017431.2017.1405069

Cited by 10 publications

(5 citation statements)

References 21 publications

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“…Physical activity is dramatically reduced due to colder temperatures especially in older individuals, which favours prothrombotic changes [1,2,15,19,22,23]. Respiratory infections such as bronchitis, pneumonia and acute exacerbation of COPD are more prevalent in the winter months and accompanied by inflammatory states, which could contribute to development of venous thromboembolism [15,19,[29][30][31][32]. In summary, it has to be hypothesised that changes in coagulation system, inflammation/infections, comorbidities as well as peripheral vasoconstrictions with reduction of blood flow in the legs increase the risk of deep vein thrombosis and PE in the winter seasons [15,22,26].…”

Section: Seasonal Differences Regarding In-hospital Mortality Ratementioning

confidence: 99%

“…Another explanation focuses on air pollution [21,26]. Air pollution seems to have an effect on pulmonary diseases, the coagulation system and on platelet function [26,31,33,34]. Air pollutants are elevated predominantly in the colder season of winter and might therefore contribute to the seasonal variation and the higher incidence of acute cardiovascular events such as deep vein thrombosis and PE [19,26,32,33,35,36].…”

Section: Seasonal Differences Regarding In-hospital Mortality Ratementioning

confidence: 99%

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Sex-specific and age-related seasonal variations regarding incidence and in-hospital mortality of pulmonary embolism in Germany

et al. 2020

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BackgroundStudies have reported seasonal variations regarding the incidence and the short-term mortality of pulmonary embolism (PE). The aim of this study was to identify sex-specific and age-related differences in seasonal patterns regarding hospitalisations and mortality of PE patients.MethodsWe analysed the impact of seasons on incidence and in-hospital mortality of male and female hospitalised PE patients in Germany (2005–2015) based on the German nationwide inpatient sample.ResultsThe German nationwide inpatient sample comprised 885 806 hospitalisations due to PE (2005–2015). Seasonal variations of both incidence (p=0.021) and in-hospital mortality (p<0.001) were of significant magnitude. Quarterly annual incidence (25.5 versus 23.7 of 100 000 citizens per year, p=0.021) and in-hospital mortality (17.0% versus 16.7%, p=0.008) were higher in winter than in summer. Risk of in-hospital mortality in winter was slightly higher (OR 1.03 (95% CI 1.01–1.06), p=0.015) compared to summer, independently of sex, age and comorbidities. Additionally, we observed sex-specific differences during seasons: the highest number of hospitalisations of PE patients of both sexes was during winter, whereas the nadir of male patients was in spring and that of female patients was in summer. Both sexes showed a maximum of in-hospital mortality in spring. Seasonal variation regarding incidence and mortality was pronounced in older patients.ConclusionIncidence and the in-hospital mortality of PE patients showed a significant seasonal variation with sex-specific differences. Although it has to be hypothesised that the seasonal variation of PE is multifactorially dependent, variation in each season was not explained by seasonal differences regarding age, sex and the prevalence of important comorbidities.

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Section: Seasonal Differences Regarding In-hospital Mortality Ratementioning

confidence: 99%

Section: Seasonal Differences Regarding In-hospital Mortality Ratementioning

confidence: 99%

Sex-specific and age-related seasonal variations regarding incidence and in-hospital mortality of pulmonary embolism in Germany

et al. 2020

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“…The presented results from our analysis correlate nitric oxide air pollution with chronic coronary syndrome, indicating progressive atherosclerotic plaque development. This novel finding broadens the scientific perspective on the pathophysiology of coronary culprit lesion and, in contrary to previous reports, suggests the relationship between meteorological factors and acute coronary syndrome risk [44,45]. More interestingly, Diaz-Chiron et al [46] presented the results of myocardial infarct size in relation to nitric oxide air and pollution and inflammatory activation measured by the neutrophil-to-lymphocyte ratio.…”

Section: Discussionmentioning

confidence: 76%

Long-Term Exposure of Nitrogen Oxides Air Pollution (NO2) Impact for Coronary Artery Lesion Progression—Pilot Study

Urbanowicz,

Skotak,

Filipiak

et al. 2023

JPM

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Background: The potentially harmful effects of air pollution on the human health have been already presented in epidemiological studies, suggesting a strong association with increased morbidity and mortality. The aim of the study was to evaluate a possible relationship between coronary artery lesion progression related to habitation place (cities vs. villages) and air pollution. Methods: There were 148 (101 men and 47 women) patients with a median age of 70 (63–74) years enrolled into retrospective analysis based on the coronary angiography results and their habitation place. Patients with stable coronary syndrome, who underwent repeated percutaneous coronary interventions were enrolled into the analysis based on demographical and clinical characteristics combined with annual exposure to air pollution (PM2.5, PM10, and NO2). Results: The results of multivariable regression analysis showed a significant relationship between coronary artery lesion progression requiring percutaneous intervention and NO2 chronic exposure in patients living in cities of Poland (OR 2.00, 95% CI: 0.41–9.62, p < 0.001). The predictive value of air pollution exposure at habitation place for coronary artery lesion disease progression requiring percutaneous intervention was evaluated by receiver-operator curve analysis, which revealed an area under the curve of 0.939, yielding a sensitivity of 87.1% and specificity of 90.7%. Conclusions: Coronary artery lesion disease progression can be related to chronic exposure to NO2 air pollution in patients living in cities in Poland.

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“…Increased LA volume is well-established as a measure of longstanding high filling pressure secondary to increased LV end-diastolic pressure. When indexed to body surface area, four of the five studies found no gender or age-related difference in LA maximum volume or LA total emptying volume ( Table 8 and Table 9 ) [ 47 , 48 , 49 , 50 , 51 ]. With ageing, however, the LA passive emptying volume and conduit volume decrease while the active emptying volume increases ( Table 10 and Table 11 ) [ 52 , 53 ].…”

Section: Resultsmentioning

confidence: 99%

Left Ventricular Diastolic Function Studied with Magnetic Resonance Imaging: A Systematic Review of Techniques and Relation to Established Measures of Diastolic Function

et al. 2021

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Purpose: In recent years, cardiac magnetic resonance (CMR) has been used to assess LV diastolic function. In this systematic review, studies were identified where CMR parameters had been evaluated in healthy and/or patient groups with proven diastolic dysfunction or known to develop heart failure with preserved ejection fraction. We aimed at describing the parameters most often used, thresholds where possible, and correlation to echocardiographic and invasive measurements. Methods and results: A systematic literature review was performed using the databases of PubMed, Embase, and Cochrane. In total, 3808 articles were screened, and 102 studies were included. Four main CMR techniques were identified: tagging; time/volume curves; mitral inflow quantification with velocity-encoded phase-contrast sequences; and feature tracking. Techniques were described and estimates were presented in tables. From published studies, peak change of torsion shear angle versus volume changes in early diastole (−dφ′/dV′) (from tagging analysis), early peak filling rate indexed to LV end-diastolic volume <2.1 s−1 (from LV time-volume curve analysis), enlarged LA maximal volume >52 mL/m2, lowered LA total (<40%), and lowered LA passive emptying fractions (<16%) seem to be reliable measures of LV diastolic dysfunction. Feature tracking, especially of the atrium, shows promise but is still a novel technique. Conclusion: CMR techniques of LV untwisting and early filling and LA measures of poor emptying are promising for the diagnosis of LV filling impairment, but further research in long-term follow-up studies is needed to assess the ability for the parameters to predict patient related outcomes.

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Impact of climate and air pollution on acute coronary syndromes: an update from the European Society of Cardiology Congress 2017

Cited by 10 publications

References 21 publications

Sex-specific and age-related seasonal variations regarding incidence and in-hospital mortality of pulmonary embolism in Germany

Sex-specific and age-related seasonal variations regarding incidence and in-hospital mortality of pulmonary embolism in Germany

Long-Term Exposure of Nitrogen Oxides Air Pollution (NO2) Impact for Coronary Artery Lesion Progression—Pilot Study

Left Ventricular Diastolic Function Studied with Magnetic Resonance Imaging: A Systematic Review of Techniques and Relation to Established Measures of Diastolic Function

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