Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review

Srinivasamurthy, Suresh Kumar; Ashokkumar, Ramkumar; Kodidela, Sunitha; Howard, Scott C.; Samer, Caroline Flora; Uppugunduri, Chakradhara Rao S.

doi:10.1007/s00228-021-03099-9

Cited by 9 publications

(5 citation statements)

References 41 publications

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“…And this finding is consistent with the current study-related finding in which the majority of prescriptions were not computerized which led to the problem of look-alike drugs (7.97%), and the absence of or unclear administration technique (12.88%). a recent review showed that the probability of error occurrence decreased by percent varied from a study to another (<1% to 33%) when a CPOE order was processed ( Srinivasamurthy et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Assessment and analysis of outpatient medication errors related to pediatric prescriptions

Kassem

Saeed

El-Bassiouny

et al. 2021

Saudi Pharmaceutical Journal

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Background Medication errors are the errors that impact the efficacy and safety of the therapy. The impact of medication errors is higher for certain subjects, such as pediatrics, who require more attention. Hence, the current study aimed to investigate the types and frequency of outpatient medication errors of pediatric subjects related to different prescription types. Methods A cross-sectional study was carried in several community pharmacies to record the medication errors found in outpatient pediatric prescriptions by gathering data from the outpatient prescriptions besides direct counseling with the subjects and their parents. Many medical resources (disease and drug-related) were used for checking the different aspects of medication errors. The data collection process included a preprepared sheet containing several items representing the medication errors in addition to a counseling session. Data were expressed as percentages and compared through the Chi-square test for results of handwritten and computerized prescriptions. Results 752 outpatient pediatric prescriptions were recruited in the study as they involve medication errors. Among the highest percentage of medication errors was the absence of essential data in the prescription, such as diagnosis, age, and weight. The duration of the therapy and contraindication for some of the prescribed medications were among the highest recorded errors. Among the critical errors were the drug interaction and drug duplication that directly affect the drug's efficacy and safety. There was a significant difference between computerized and handwritten prescriptions regarding the number of medication errors related to each type. Conclusion Medication errors related to outpatient pediatric prescriptions vary from one to another prescription with predominant errors that influence the therapy's safety or efficacy. The role of patient counseling and prescription checking is critical for improving patient therapy.

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Section: Discussionmentioning

confidence: 99%

Assessment and analysis of outpatient medication errors related to pediatric prescriptions

Kassem

Saeed

El-Bassiouny

et al. 2021

Saudi Pharmaceutical Journal

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“…The submitted orders are transmitted through a computer network to the medical staff or the departments (pharmacy, laboratory, or radiology) tasked with fulfilling the request. CPOE decreases the time required to distribute and complete orders while enhancing efficiency by reducing transcribing errors and preventing duplicate order entries, as well as by expediting inventory management and billing services [ 43 ].…”

Section: Ehealth: An Overviewmentioning

confidence: 99%

eHealth: A Survey of Architectures, Developments in mHealth, Security Concerns and Solutions

Alenoghena

Onumanyi

Ohize

et al. 2022

IJERPH

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The ramifications of the COVID-19 pandemic have contributed in part to a recent upsurge in the study and development of eHealth systems. Although it is almost impossible to cover all aspects of eHealth in a single discussion, three critical areas have gained traction. These include the need for acceptable eHealth architectures, the development of mobile health (mHealth) technologies, and the need to address eHealth system security concerns. Existing survey articles lack a synthesis of the most recent advancements in the development of architectures, mHealth solutions, and innovative security measures, which are essential components of effective eHealth systems. Consequently, the present article aims at providing an encompassing survey of these three aspects towards the development of successful and efficient eHealth systems. Firstly, we discuss the most recent innovations in eHealth architectures, such as blockchain-, Internet of Things (IoT)-, and cloud-based architectures, focusing on their respective benefits and drawbacks while also providing an overview of how they might be implemented and used. Concerning mHealth and security, we focus on key developments in both areas while discussing other critical topics of importance for eHealth systems. We close with a discussion of the important research challenges and potential future directions as they pertain to architecture, mHealth, and security concerns. This survey gives a comprehensive overview, including the merits and limitations of several possible technologies for the development of eHealth systems. This endeavor offers researchers and developers with a quick snapshot of the information necessary during the design and decision-making phases of the eHealth system development life cycle. Furthermore, we conclude that building a unified architecture for eHealth systems would require combining several existing designs. It also points out that there are still a number of problems to be solved, so more research and investment are needed to develop and deploy functional eHealth systems.

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“…Studies have reported up to a 40-fold decrease in errors that could cause harm with the use of CPOE compared with handwritten order entry. 4 In addition, a systematic review of 11 academic institutions globally found an 81% reduction in anticancer therapy medication errors following CPOE implementation. 4,5 Institutions that have implemented CPOE systems have also found a reduction in the number of medication errors.…”

Section: Introductionmentioning

confidence: 99%

“…4 In addition, a systematic review of 11 academic institutions globally found an 81% reduction in anticancer therapy medication errors following CPOE implementation. 4,5 Institutions that have implemented CPOE systems have also found a reduction in the number of medication errors. 3,6 The ISMP recommends that independent review for all hazardous medications should not be broadly applied, but rather based on institution-specific workflows.…”

Section: Introductionmentioning

confidence: 99%

Evaluating the Impact of Pharmacist Dual Verification of Anticancer Therapy in the Modern Era

Stonerock,

Clark,

Shah

et al. 2023

Journal of Pharmacy Technology

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Background: Pharmacist order verification is a critical step in ensuring medication safety for patients. While the second pharmacist verification (SPV) before dispensing anticancer therapies has been a longstanding practice, its continued necessity in the context of modern electronic health systems lacks robust evidence. Objective: This study aimed to assess the frequency of interventions performed by a second pharmacist to determine the ongoing effectiveness of the SPV process. Methods: This retrospective chart review was conducted at the Mayo Clinic, encompassing all anticancer therapy orders that necessitated an SPV. The study period extended from January 1, 2019, to June 30, 2021, and included inpatient and outpatient anticancer orders. The quantification and reporting of alterations made to discrete order fields subsequent to initial pharmacist verification of clinical significance were performed, utilizing the total number of anticancer therapy orders as the denominator. Results: Approximately 300 000 anticancer therapy orders were screened for inclusion criteria and 2.6% (N = 7634) of orders were modified on the SPV. Most changes were in the categories of rate (N = 1962), order start time (N = 1219), and pharmacy communication note (N = 777). Dosing changes greater than 10% accounted for 0.03% (N = 99) of the orders, with 10 anticancer therapies responsible for more than 50% of these changes. Conclusion and relevance: This study represents the largest report on the impact of SPV in a modern era. Our results suggest the SPV may be valuable for a small proportion of chemotherapy orders but raises questions about the necessity for broad application of this practice.

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Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review

Cited by 9 publications

References 41 publications

Assessment and analysis of outpatient medication errors related to pediatric prescriptions

Assessment and analysis of outpatient medication errors related to pediatric prescriptions

eHealth: A Survey of Architectures, Developments in mHealth, Security Concerns and Solutions

Evaluating the Impact of Pharmacist Dual Verification of Anticancer Therapy in the Modern Era

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