Impact of Continuous Deterioration of Kidney Function 6 to 8 Months After Percutaneous Coronary Intervention for Acute Coronary Syndrome

Nemoto, Nobukatsu; Iwasaki, Masaki; Nakanishi, Mami; Araki, Tadashi; Utsunomiya, Makoto; Hori, Masaki; Ikeda, Nobutaka; Makino, Kunihiko; Itaya, Hideki; Iijima, Raisuke; Hara, Hidehiko; Takagi, Toshio; Joki, Nobuhiko; Sugi, Kaoru; Nakamura, Masato

doi:10.1016/j.amjcard.2014.02.019

Cited by 40 publications

(34 citation statements)

References 28 publications

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“…In this study, overall incidence of CI-AKI was found to be 12%, and persistent renal dysfunction was found in 18.6% of CI-AKI patients. Similarly, in another study performed on patients undergoing PTCA, continuous deterioration of kidney function (CDKF) was defined as > 25% increase in serum creatinine or serum creatinine > 0.5 mg/dL above baseline at 6 to 8 mo after PTCA[4]. In this study CDFK was found in 16% of the study population and this group of patients was found to have significantly higher 5-year mortality rate.…”

Section: Prognosis Of Ci-akimentioning

confidence: 73%

“…In the past, CI-AKI was considered to be a mild state with asymptomatic and transient elevations in serum creatinine values however recent studies have demonstrated that both short term and long-term mortality rates have been found to be significantly higher in patients with CI-AKI compared to patients without CI-AKI[2]. Furthermore, a history of CI-AKI may be associated with development of chronic kidney disease (CKD) and progression to end-stage renal disease (ESRD) in long term[3,4]. …”

Section: Introductionmentioning

confidence: 99%

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Contrast-induced acute kidney injury: A review of practical points

Özkök¹,

Özkök²

2017

WJN

122

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Contrast-induced acute kidney injury (CI-AKI) is one of the most common causes of AKI in clinical practice. CI-AKI has been found to be strongly associated with morbidity and mortality of the patients. Furthermore, CI-AKI may not be always reversible and it may be associated with the development of chronic kidney disease. Pathophysiology of CI-AKI is not exactly understood and there is no consensus on the preventive strategies. CI-AKI is an active research area thus clinicians should be updated periodically about this topic. In this review, we aimed to discuss the indications of contrast-enhanced imaging, types of contrast media and their impact on nephrotoxicity, major pathophysiological mechanisms, risk factors and preventive strategies of CI-AKI and alternative non-contrast-enhanced imaging methods.

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Section: Prognosis Of Ci-akimentioning

confidence: 73%

Section: Introductionmentioning

confidence: 99%

Contrast-induced acute kidney injury: A review of practical points

Özkök¹,

Özkök²

2017

WJN

122

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“…Indeed, a recent study demonstrated that a persistent deterioration of kidney function, defined as a >25% or >0.5 mg/dL increase in sCr above baseline, was still detectable between 6 and 8 months after PCI in about 40% of patients developing AKI during ACS, and that it was a strong independent predictor of 5-year mortality 42. The Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) showed that, among 14 782 patients (10 671 with ACS) undergoing coronary angiography, AKI was associated with an increased risk of death, progression to ESRD, and subsequent hospitalisation for AKI, but not of hospitalisation for AMI and cerebrovascular events, at long-term (median 19.7 months) follow-up 19…”

Section: Renal Implications Of Akimentioning

confidence: 99%

Acute kidney injury in patients with acute coronary syndromes

Marenzi

Cosentino

Bartorelli

2015

Heart

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Acute kidney injury (AKI) is increasingly being seen in patients with acute coronary syndromes (ACSs). This condition has a complex pathogenesis, an incidence that can reach 30% and it is associated with higher short-term and long-term morbidity and mortality. Nevertheless, AKI is still characterised by lack of a single accepted definition, unclear pathophysiology understanding and insensitive diagnostic tools that make its detection difficult, particularly in the setting of ACS. Recent data suggested that patients with AKI during ACS, even those in whom renal function seems to fully recover, face an increased, persisting risk of future AKI and may develop chronic kidney disease. Thus, in these patients, nephrology follow-up, after hospital discharge, and secondary preventive measures should possibly be implemented. In this review, we aim at providing a framework of knowledge to increase cardiologists' awareness of AKI, with the goal of improving the outcome of patients with ACS.

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“…In‐hospital mortality has been shown to be 20 times higher in AMI patients who experience AKI compared with those without this complication 3. Moreover, a close association has been established between AKI development during AMI and increased long‐term morbidity and mortality, persistent loss of kidney function, and risk of progression to end‐stage renal disease 4, 5…”

mentioning

confidence: 99%

Acute Kidney Injury in Diabetic Patients With Acute Myocardial Infarction: Role of Acute and Chronic Glycemia

Marenzi

Cosentino

Milazzo

et al. 2018

JAHA

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BackgroundIn acute myocardial infarction, acute hyperglycemia is a predictor of acute kidney injury (AKI), particularly in patients without diabetes mellitus. This emphasizes the importance of an acute glycemic rise rather than glycemia level at admission. We investigated whether, in diabetic patients with acute myocardial infarction, the combined evaluation of acute and chronic glycemic levels may have better prognostic value for AKI than admission glycemia.Methods and ResultsAt admission, we prospectively measured glycemia and estimated average chronic glucose levels (mg/dL) using glycosylated hemoglobin (HbA1c), according to the following formula: 28.7×HbA1c (%)−46.7. We evaluated the association with AKI of the acute/chronic glycemic ratio and of the difference between acute and chronic glycemia (ΔA−C). We enrolled 474 diabetic patients with acute myocardial infarction. Of them, 77 (16%) experienced AKI. The incidence of AKI increased in parallel with the acute/chronic glycemic ratio (12%, 14%, 22%; P=0.02 for trend) and ΔA−C (13%, 13%, 23%; P=0.01) but not with admission glycemic tertiles (P=0.22). At receiver operating characteristic analysis, the acute/chronic glycemic ratio (area under the curve: 0.62 [95% confidence interval, 0.55–0.69]; P=0.001) and ΔA−C (area under the curve: 0.62 [95% confidence interval, 0.54–0.69]; P=0.002) accurately predicted AKI, without difference in the area under the curve between them (P=0.53). At reclassification analysis, the addition of the acute/chronic glycemic ratio and ΔA−C to acute glycemia allowed proper AKI risk prediction in 16% of patients.ConclusionsIn diabetic patients with acute myocardial infarction, AKI is better predicted by the combined evaluation of acute and chronic glycemic values than by assessment of admission glycemia alone.

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Impact of Continuous Deterioration of Kidney Function 6 to 8 Months After Percutaneous Coronary Intervention for Acute Coronary Syndrome

Cited by 40 publications

References 28 publications

Contrast-induced acute kidney injury: A review of practical points

Contrast-induced acute kidney injury: A review of practical points

Acute kidney injury in patients with acute coronary syndromes

Acute Kidney Injury in Diabetic Patients With Acute Myocardial Infarction: Role of Acute and Chronic Glycemia

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