Impact of Coronary Artery Calcium Characteristics on Accuracy of CT Angiography

Kruk, Mariusz; Noll, Dariusz; Achenbach, Susanne; Mintz, Gary S.; Pręgowski, Jerzy; Kaczmarska, Edyta; Kryczka, Karolina; Pracoń, Radosław; Dzielińska, Zofia; Śleszycka, Justyna; Witkowski, Adam; Demkow, Marcin; Rużyłło, Witold; Kępka, Cezary

doi:10.1016/j.jcmg.2013.07.013

Cited by 85 publications

(53 citation statements)

References 23 publications

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“…50 Coronary computed tomography angiography (CCTA) is an appealing option but detection remains limited to those without significant coronary calcifications. 100 Combination with perfusion imaging may help overcome these limitations and increases the yield of CCTA. 101 Radiation exposure has been a concern but recently developed CT scanners have led to dose reduction.…”

Section: Introductionmentioning

confidence: 99%

Evaluation and Management of Patients With Heart Disease and Cancer: Cardio-Oncology

Herrmann

Lerman

Sandhu

et al. 2014

Mayo Clinic Proceedings

354

289

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The care for patients with cancer has advanced greatly over the past decades. A combination of earlier cancer diagnosis and greater use of traditional and novel systemic treatments has decreased cancer-related mortality. Effective cancer therapies, however, can result in short- and long-term co-morbidities that can decrease the net clinical gain by impacting quality of life and survival. In particular, cardiovascular complications of cancer treatments can have a profound impact on the health of cancer patients and are more common among those with recognized or unrecognized underlying cardiovascular diseases. A new discipline termed “cardio-oncology” has thus evolved to address the cardiovascular needs of cancer patients and optimize their care in a multidisciplinary approach. This review provides a brief introduction and background on this emerging field and then focuses on its practical aspects including: cardiovascular risk assessment and prevention before cancer treatment, cardiovascular surveillance and therapy during cancer treatment, and cardiovascular monitoring and management after cancer therapy. The content of this review is based on a literature search of PubMed between January 1, 1960, and February 1, 2014 using the search terms cancer, cardiomyopathy, cardiotoxicity, cardio-oncology, chemotherapy, heart failure, and radiation.

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Section: Introductionmentioning

confidence: 99%

Evaluation and Management of Patients With Heart Disease and Cancer: Cardio-Oncology

Herrmann

Lerman

Sandhu

et al. 2014

Mayo Clinic Proceedings

354

289

View full text Add to dashboard Cite

show abstract

“…N oninvasive anatomic assessment by coronary computed tomography angiography (CTA) shows high diagnostic performance for the detection or exclusion of coronary artery disease (CAD) (1)(2)(3)(4)(5)(6)(7)(8). However, coronary CTA has only modest accuracy regarding the quantification of stenosis severity, particularly in the setting of coronary calcification.…”

mentioning

confidence: 99%

“…The presence of calcified coronary lesions often leads to overestimation of stenosis severity due to blooming and beam-hardening artifacts obscuring the vessel lumen. Thus, the presence of coronary calcification is associated with reduced diagnostic specificity of coronary CTA (1)(2)(3)(4)(5)(6)(7)(8). Moreover, coronary CTA, in its current form, has a limited capacity to determine the hemodynamic significance of coronary stenosis (9)(10)(11)(12).…”

mentioning

confidence: 99%

Influence of Coronary Calcification on the Diagnostic Performance of CT Angiography Derived FFR in Coronary Artery Disease

Nørgaard¹,

Gaur²,

Leipsic³

et al. 2015

JACC: Cardiovascular Imaging

160

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“…CTCA has shown high accuracy for the detection of obstructive CAD (table 2),19–22 although overestimation of coronary obstruction may occur in patients with extensive coronary calcification 19 23. Accordingly, CTCA is most useful for excluding obstructive CAD in low-risk subjects, particularly those presenting for evaluation of acute symptoms.…”

Section: Applications Of Cctmentioning

confidence: 99%