Impact of COVID-19 pandemic on the rates of central line...associated bloodstream infection and catheter-associated urinary tract infection in an.ßintensive care setting:.ßNational experience

Coronavirus disease 2019 (COVID-19) impact on central-line-associated bloodstream infections (CLABSI): a systematic review

“…The authors also commented that the strict adherence to IPC measures had probably an impact in reducing the event of DAIs, but their results could not be generalized as limited to a single hospital. This is in line with another Saudi Arabian study from an hospital network with five ICUs [ 16 ], where they also recorded no difference in the CLABSI rates, but in contrast with a national analysis including all the Ministry of Health hospitals [ 32 ] where the COVID-19 pandemic was associated with increased CLABSI rates.…”

“…, 2022 [ 19 ] COVID-19 Healthcare associated infections (HAI), including central-line-associated bloodstream infections (CLABSI), catheter-associated urinary tract infections (CAUTI), Clostridioides difficile infections (CDI), and ventilator-associated events (VAE) USA Retrospective longitudinal multicenter cohort study 53 hospitals in Southeastern United States CLABSI increased by 24%, during the pandemic period On stratifying the analysis by hospital characteristics, the impact of the pandemic on HCAIs was more significant in smaller community hospitals Increase AlAhdal et al. , 2022 [ 15 ] COVID-19 Device associated infections (DAI), compliance with hand hygiene and other prevention bundles in ICU Saudi Arabia Retrospective observational study Single 500-bed hospital, including 80 adult ICU beds There was no significant difference in the number of device associated infections or compliance with hand hygiene and other bundles No difference Alsaffar [ 32 ] COVID-19 CLABSI and CAUTI data Saudi Arabia Retrospective data analysis Data from the Saudi Health Electronic Surveillance Network (HESN) covering Ministry of Health Hospitals The COVID-19 pandemic was associated with increased CLABSI rates Increase Al-Tawfig [ 16 ] COVID-19 VAE, CAUTI and CLABSI data Saudi Arabia Retrospective data analysis Hospital network with 5 ICUs No significant difference observed for CLABSI (but limited to 2020 only) No difference Baker et al. , 2022 [ 17 ] COVID-19 CLABSI, CAUTI, methicillin-resistant Staphylococcus aureus (MRSA) bacteremias, and Clostridioides difficile infections (CDI) USA Prospective cohort study 148 hospitals affiliated with the Health Corporation of America (HCA) CLABSI and MRSA bacteraemias increased during the COVID pandemic Increase Ben-Aderet et al.…”

Central Line Associated Bloodstream Infections in Critical Ill Patients during and before the COVID-19 Pandemic

“…Our study highlights a higher rate of CLABSI during the COVID-19 surge compared with the pre-pandemic period in ICU patients. Our findings are consistent with previous studies conducted in many healthcare settings [12,13,[25][26][27]. For example, analyses conducted in US NHSN hospitals showed 37-51% increases in CLABSI rates during the COVID-19 pandemic.…”

“…According to their and other results, larger hospitals (>300 beds), as well as ours, were most affected [13,25]. Comparable studies show an increase in CLABSI rate by 280% in tertiary care hospitals in Detroit [28], a 60% increase in HCA Healthcareaffiliated hospitals [25], an 86% in INNIC developing countries [26], and a 16% increase were reported in Saudi Arabia [12]. In our study, we also analyzed CLABSI rates in patients with and without COVID-19 during the COVID-19 pandemic.…”

“…Many studies showed a significant increase in CLABSI rates during the COVID-19 pandemic [12][13][14]. Other studies did not find a significant impact of the COVID-19 pandemic on the rates of HAI [15,16].…”