Impact of COVID-19 Pandemic on the Outcomes of Acute Coronary Syndrome

Alharbi, Abdulmajeed; Franz, Allison; Alfatlawi, Halah; Wazzan, Mohaamed; Alsugher, Anas; Eltahawy, Ehab; Assaly, Ragheb

doi:10.1016/j.cpcardiol.2022.101575

Cited by 9 publications

(8 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Among hospitalized patients with COVID-19, the mortality has been reported to be approximately 21% [ 30 ]. The frequency of COVID-19 in patients treated for STEMI reached up to 1% in epidemiological studies [ 31 , 32 ]. In our study it was 2.5%.…”

Section: Discussionmentioning

confidence: 99%

The Influence of SARS-CoV-2 Infection on Acute Myocardial Infarction Outcomes

Hrycek,

Walawska-Hrycek,

Hamankiewicz

et al. 2023

JCM

View full text Add to dashboard Cite

Background: This multicenter retrospective study with a control group was designed to assess the influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the outcomes of patients with myocardial infarction (MI). Methods: A total of 129 patients with COVID-19 who were treated for MI were included in this study. The control group comprised 129 comparable patients without SARS-CoV-2 infection. The in-hospital, out-of-hospital, and overall mortality were analyzed. Results: A total of thirty-one (24%) patients died in the study group, and two (1.6%) patients died in the control group (OR = 20.09; CI: 4.69–85.97; p < 0.001). Similar results were observed in all analyzed patient subgroups. Multivariable Cox regression analysis confirmed the significant influence of SARS-CoV-2 infection on in-hospital outcomes (HR: 8.48459; CI: 1.982–36.320; p = 0.004). Subanalysis of the groups with COVID-19 plus ST-elevation MI (STEMI) or non-ST-elevation MI (NSTEMI) revealed comparable mortality rates: 14 (21.12%) patients in the NSTEMI group and 17 (26.98%) patients in the STEMI subgroup died (OR: 1.3; CI: 0.56–3.37; p = 0.45). During out-of-hospital observation, no differences in mortality were observed (OR: 0.77; CI: 0.11–4.07; p = 0.73). Conclusions: SARS-CoV-2 infection affects the in-hospital outcomes of patients with both MI and COVID-19, regardless of MI type (STEMI vs. NSTEMI).

show abstract

Section: Discussionmentioning

confidence: 99%

The Influence of SARS-CoV-2 Infection on Acute Myocardial Infarction Outcomes

Hrycek,

Walawska-Hrycek,

Hamankiewicz

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

“…In-hospital mortality and heart failure showed a rising trend in successfully treated STEMI patients during the outbreak possibly due to delayed reperfusion by almost 20 minutes on average [ 46 ]. A study has shown that patients with STEMI and COVID-19 had higher hospital charges and a longer time from admission to PCI compared to those without COVID-19 [ 47 ]. Several studies have also reported poorer outcomes for STEMI patients with a concomitant COVID-19 diagnosis compared to historical control patients, including higher mortality rates, longer length of stay, and an increased risk of stent thrombosis [ 44 ].…”

Section: Reviewmentioning

confidence: 99%

Multifaceted Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on ST-Elevation Myocardial Infarction (STEMI): A Literature Review of Incidence, Treatment Modalities, and Outcomes

Choi,

Maity,

Qureshi

et al. 2024

Cureus

View full text Add to dashboard Cite

The global repercussions of coronavirus disease 2019 (COVID-19) include substantial worldwide mortality and have brought to light existing gaps in healthcare systems. Particularly, diseases requiring time-sensitive treatment, such as ST-elevation myocardial infarction (STEMI), have faced significant challenges due to the impact and revelations of the COVID-19 pandemic on healthcare infrastructure. This review addresses the impact of the pandemic on STEMI, exploring incidence, treatment modalities, and clinical outcomes. Through a critical examination of existing literature, the intricate relationship between the pandemic and cardiovascular health, specifically STEMI, is elucidated. The COVID-19 pandemic has had a significant impact on the management of STEMI, with changes in hospitalization rates, treatment strategies, and the presentation of the disease posing significant challenges. The contradictory results of COVID-19 and post-vaccine myocardial infarction, as well as gender differences in reported cases, highlight the need for further research to clarify these relationships.

show abstract

“…смертей, зафіксований у 2003 році [1,2,3]. Зокрема відзначено значне збільшення смертності від гострого інфаркту міокарда (ГІМ) з елевацією сегмента ST під час пандемії 5,6].Продовжуються роботи з дослідження патофізіологічних механізмів порушення функції вегетативної нервової системи (ВНС) у хворих з ішемічною хворобою серця (ІХС) у поєднанні з COVID-19. Показово, що…”

unclassified

“…Обговорення. Незважаючи на відомий негативний вплив COVID-19 на прогноз у пацієнтів із серцево-судинними захворюваннями [1,2,3,4,5,6], нині існує потреба у доповненні уявлень про патофізіологію ураження серцево-судинної системи при інфікуванні SARS-CoV-2, зокрема шляхом вивчення змін та взаємозв'язків структурно-функціонального стану міо карда та ВСР у хворих із супутньою ІХС.…”

unclassified

See 1 more Smart Citation

The Impact of COVID-19 upon Intracardiac Hemodynamics and Heart Rate Variability in Stable Coronary Artery Disease Patients

Netyazhenko

Mostovyi

Safonova

2023

ujcvs

View full text Add to dashboard Cite

The aim. To study the impact of COVID-19 upon intracardiac hemodynamics and heart rate variability (HRV) in stable coronary artery disease (SCAD) patients. Materials and methods. In this cross-sectional study we analyzed clinical and instrumental data obtained from a sample of 80 patients. The patients were divided into three groups: group 1 included patients with SCAD without COVID-19 (n=30), group 2 included patients with SCAD and COVID-19 (n=25), and group 3 included patients with COVID-19 without SCAD (n=25). The control group included 30 relatively healthy volunteers. Results. The changes in intracardiac hemodynamics and HRV in group 2 were characterized by the impaired left ventricular systolic and diastolic function, dilation of both ventricles and elevated systolic pulmonary artery pressure. Left ventricular end-diastolic volume was higher in group 2 (205±21 ml) than that in group 1 (176±33 ml; р<0.001) and group 3 (130±21 ml; р<0.001). Patients in the groups 1–3, compared to controls, presented with the decrease in the overall HRV (by standard deviation [SD] of all NN intervals [SDNN]; SD of the averages of NN intervals in all 5 min segments of the entire recording; and mean of the SDs of all NN intervals for all 5 min segments of the entire recording) and parasympathetic activity (root-mean-square difference of successive NN intervals; the proportion derived by dividing the number of interval differences of successive NN intervals greater than 50 ms [NN50] by the total number of NN intervals [pNN50], and high frequency spectral component), along with QT interval prolongation and increase in its variability. Group 2 demonstrated the most advanced changes in HRV (by SDNN and pNN50) and both QT interval characteristics. Conclusions. The patients with SCAD and concomitant COVID-19, along with both ventricles dilation and intracardiac hemodynamics impairment, presented with the sings of autonomic dysfunction, QT interval prolongation and increase in its variability. The heart rate variability and QT interval characteristics should be additionally considered in the management of such patients.

show abstract

Impact of COVID-19 Pandemic on the Outcomes of Acute Coronary Syndrome

Cited by 9 publications

References 22 publications

The Influence of SARS-CoV-2 Infection on Acute Myocardial Infarction Outcomes

The Influence of SARS-CoV-2 Infection on Acute Myocardial Infarction Outcomes

Multifaceted Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on ST-Elevation Myocardial Infarction (STEMI): A Literature Review of Incidence, Treatment Modalities, and Outcomes

The Impact of COVID-19 upon Intracardiac Hemodynamics and Heart Rate Variability in Stable Coronary Artery Disease Patients

Contact Info

Product

Resources

About