Impact of COVID-19 pandemic on flu vaccine uptake in healthcare workers in Europe: a systematic review and meta-analysis

Bianchi, Francesco Paolo; Cuscianna, Eustachio; Rizzi, Donato; Signorile, Noemi; Daleno, Antonio; Migliore, Giovanni; Tafuri, Silvio

doi:10.1080/14760584.2023.2250437

Cited by 3 publications

(1 citation statement)

References 50 publications

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“…Among high-risk respondents, 21% gave no specific reason for not receiving an influenza vaccine, and 15.3% said they "did not get around to it" [17]. This finding is generally consistent with other recent surveys among Canadians, even as vaccine hesitancy remains high in other populations [14,[20][21][22][23].…”

Section: Discussionsupporting

confidence: 85%

Co-Administration of Influenza and COVID-19 Vaccines: A Cross-Sectional Survey of Canadian Adults’ Knowledge, Attitudes, and Beliefs

Houle,

Johal,

Roumeliotis

et al. 2024

Pharmacy

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Vaccination rates against both influenza and COVID-19 fall short of targets, especially among persons at risk of influenza complications. To gain insights into strategies to boost influenza vaccine coverage, we surveyed 3000 Canadian residents aged ≥ 18 years and examined their knowledge and receipt of co-administered influenza and COVID-19 vaccines. During the 2022–2023 influenza season, 70% of respondents reported being aware the influenza and COVID-19 vaccines could be co-administered, but only 26.2% (95% CI, 23.6% to 28.8%) of respondents received them together. The most common reason for not getting the vaccines together was receipt of the COVID-19 vaccine before the annual influenza vaccine was available (reported by 34.5% [31.2% to 37.7%]). Lack of interest in co-administration was reported by 22.6% (20.8% to 24.3%); of this group, 20.8% (17.1% to 24.5%) reported seeing no benefit in receiving the two vaccines together and 17.2% (13.5% to 20.9%) were concerned about compounded adverse effects from the two vaccines. These results support the willingness of most Canadians to receive COVID-19 and influenza vaccines at the same time. Co-administration is a viable strategy to improve uptake of influenza vaccines, especially if health professionals proactively offer education and co-administration of influenza and COVID-19 (or other) vaccines as appropriate to clinical need.

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Section: Discussionsupporting

confidence: 85%

Co-Administration of Influenza and COVID-19 Vaccines: A Cross-Sectional Survey of Canadian Adults’ Knowledge, Attitudes, and Beliefs

Houle,

Johal,

Roumeliotis

et al. 2024

Pharmacy

View full text Add to dashboard Cite

show abstract

The impact of the COVID-19 pandemic and the free vaccination policy on seasonal influenza vaccination uptake among older adults in Ningbo, Eastern China

Ye,

Chen,

Mei

et al. 2024

Human Vaccines & Immunotherapeutics

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Evidence base for yearly respiratory virus vaccines: Current status and proposed improved strategies

Barosa,

Ioannidis,

Prasad

2024

Eur J Clin Investigation

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Annual vaccination is widely recommended for influenza and SARS‐CoV‐2. In this essay, we analyse and question the prevailing policymaking approach to these respiratory virus vaccines, especially in the United States. Every year, licensed influenza vaccines are reformulated to include specific strains expected to dominate in the season ahead. Updated vaccines are rapidly manufactured and approved without further regulatory requirement of clinical data. Novel vaccines (i.e. new products) typically undergo clinical trials, though generally powered for clinically unimportant outcomes (e.g. lab‐confirmed infections, regardless of symptomatology or antibody levels). Eventually, the current and future efficacy of influenza and COVID‐19 vaccines against hospitalization or death carries considerable uncertainty. The emergence of highly transmissible SARS‐CoV‐2 variants and waning vaccine‐induced immunity led to plummeting vaccine effectiveness, at least against symptomatic infection, and booster doses have since been widely recommended. No further randomized trials were performed for clinically important outcomes for licensed updated boosters. In both cases, annual vaccine effectiveness estimates are generated by observational research, but observational studies are particularly susceptible to confounding and bias. Well‐conducted experimental studies, particularly randomized trials, are necessary to address persistent uncertainties about influenza and COVID‐19 vaccines. We propose a new research framework which would render results relevant to the current or future respiratory viral seasons. We demonstrate that experimental studies are feasible by adopting a more pragmatic approach and provide strategies on how to do so. When it comes to implementing policies that seriously impact people's lives, require substantial public resources and/or rely on widespread public acceptance, high evidence standards are desirable.

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Impact of COVID-19 pandemic on flu vaccine uptake in healthcare workers in Europe: a systematic review and meta-analysis

Cited by 3 publications

References 50 publications

Co-Administration of Influenza and COVID-19 Vaccines: A Cross-Sectional Survey of Canadian Adults’ Knowledge, Attitudes, and Beliefs

Co-Administration of Influenza and COVID-19 Vaccines: A Cross-Sectional Survey of Canadian Adults’ Knowledge, Attitudes, and Beliefs

The impact of the COVID-19 pandemic and the free vaccination policy on seasonal influenza vaccination uptake among older adults in Ningbo, Eastern China

Evidence base for yearly respiratory virus vaccines: Current status and proposed improved strategies

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