2023
DOI: 10.3389/fcimb.2023.1295311
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Impact of CRAMP-34 on Pseudomonas aeruginosa biofilms and extracellular metabolites

Shiyuan Wang,
Chengjun Ma,
Jinying Long
et al.

Abstract: Biofilm is a structured community of bacteria encased within a self-produced extracellular matrix. When bacteria form biofilms, they undergo a phenotypic shift that enhances their resistance to antimicrobial agents. Consequently, inducing the transition of biofilm bacteria to the planktonic state may offer a viable approach for addressing infections associated with biofilms. Our previous study has shown that the mouse antimicrobial peptide CRAMP-34 can disperse Pseudomonas aeruginosa (P. aeruginosa) biofilm, a… Show more

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