Impact of creatinine values on MELD scores in male and female candidates for liver transplantation

Mariante-Neto, Guilherme; Marroni, Caroline Possa; Fleck, Alfeu de Medeiros; Marroni, Cláudio Augusto; Zanotelli, Maria Lúcia; Cantisani, Guido Pio Gracco; Brandão, Ajácio

doi:10.1016/s1665-2681(19)31006-3

Cited by 15 publications

(11 citation statements)

References 17 publications

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“…However, this remains controversial. Of note, Mariante-Neto et al did not observe any differences in survival and chance for transplant between sexes in a similar study design 18 and the study by Umemura et al even documented a better survival for female patients 19 .…”

Section: Introductionmentioning

confidence: 78%

Nosocomial infections in female compared with male patients with decompensated liver cirrhosis

Griemsmann

Tergast

Simon

et al. 2022

Sci Rep

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There are considerable differences between males and females regarding the etiology, progression and outcome of liver diseases. Infections are a frequent and severe complication in these patients. This study aimed to examine sex specific differences in the incidence and clinical course of nosocomial infections in patients with decompensated liver cirrhosis. A number of 556 consecutive hospitalized patients with decompensated liver cirrhosis and ascites were analyzed. The patients were followed up for the incidence of nosocomial infections, acute kidney injury (AKI), acute-on-chronic liver failure (ACLF) as well as liver transplantation and death (LTx-free survival). A number of 285 patients (111 women and 174 men) developed a nosocomial infection. Incidence was numerically lower in men (P = 0.076). While the frequency of a nosocomial spontaneous bacterial peritonitis was similar between males and females, the incidence of a nosocomial urinary tract infection was significantly higher in women (P < 0.001). No sex specific differences were documented regarding the outcome of an infection as indicated by a similar incidence of, AKI, ACLF as well as LTx-free survival. There seem to be no major differences in the incidence and outcome of nosocomial infections between male and female patients.

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Section: Introductionmentioning

confidence: 78%

Nosocomial infections in female compared with male patients with decompensated liver cirrhosis

Griemsmann

Tergast

Simon

et al. 2022

Sci Rep

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“…The MDRD formula has not been validated in end-stage liver disease patients, but, despite its flaws, has been used in similar analyzes elsewhere. 7,19,20,24,28 As of Brazil's 2010 Census, 29 in the state of Rio Grande do Sul, where this research was conducted, 83.2% of the population identified themselves as white, 10.6% as brown, and 5.6% as black. However, evidence suggests that selfreported skin color was not correlated with genetic ancestry in admixed populations, such as the Brazilian one.…”

Section: Discussionmentioning

confidence: 95%

Model for End-Stage Liver Disease

Mariante-Neto

Brandão²

2015

Transplantation

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“…Mariante-Neto, et al21 and Romano, et al22 reported that lower levels of creatinine may influence the low prognostic value of MELD score, which is associated post-ERCP bleeding, and suggested that sex may have an impact on the prognostic value of both MELD and CP scores. Herein, we matched all patients by age and sex.…”

Section: Discussionmentioning

confidence: 99%

Bleeding Complications and Clinical Safety of Endoscopic Retrograde Cholangiopancreatography in Patients with Liver Cirrhosis

et al. 2019

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Purpose Patients with liver cirrhosis are considered to be at risk for additional adverse events during endoscopic retrograde cholangiopancreatography (ERCP). The present study was designed as a propensity-score matched analysis to investigate whether cirrhotic liver increases the risk of bleeding complications in patients undergoing ERCP. Materials and Methods In total, 8554 patients who underwent ERCP from January 2005 to December 2015 were retrospectively analyzed. To adjust for the imbalance between patients with and those without liver cirrhosis, 1:3 propensity score matching was performed according to age and sex. Results Liver cirrhosis was identified in 264 (3.1%) patients. After propensity score matching, a total of 768 patients were included in each of the cirrhotic (n=192) and non-cirrhotic groups (n=576). Post-procedure bleeding (10.9% vs. 4.7%, p =0.003) was more frequently observed in patients with liver cirrhosis than in those without. In multivariate analyses, liver cirrhosis was identified as an independent risk factor associated with post-ERCP bleeding ( p =0.003) after further adjustment for prothrombin time, antiplatelet/coagulant, duration of ERCP, and stent insertion. Child-Pugh (CP) class C was found to be associated with an increased incidence of post-ERCP bleeding in patients with cirrhosis (odds ratio 6.144, 95% confidence interval 1.320–28.606; p =0.021). Conclusion The incidence of post-ERCP bleeding in patients with liver cirrhosis was higher than that in patients without liver cirrhosis. In particular, CP class C cirrhosis was significantly associated with post-ERCP bleeding.

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Impact of creatinine values on MELD scores in male and female candidates for liver transplantation

Cited by 15 publications

References 17 publications

Nosocomial infections in female compared with male patients with decompensated liver cirrhosis

Nosocomial infections in female compared with male patients with decompensated liver cirrhosis

Model for End-Stage Liver Disease

Bleeding Complications and Clinical Safety of Endoscopic Retrograde Cholangiopancreatography in Patients with Liver Cirrhosis

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