2024
DOI: 10.1007/s40271-023-00668-1
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Impact of Difelikefalin on the Health-Related Quality of Life of Haemodialysis Patients with Moderate-To-Severe Chronic Kidney Disease-Associated Pruritus: A Single-Arm Intervention Trial

James Fotheringham,
Julian Guest,
Joerg Latus
et al.

Abstract: Objective Chronic kidney disease-associated pruritus (CKD-aP) can have a substantial negative impact on health-related quality of life (HRQoL), including an increased risk of depression, anxiety and sleep disturbance. This trial aimed to assess the impact of intravenous difelikefalin on HRQoL in haemodialysis patients with moderate-to-severe CKD-aP. Methods Post hoc analysis of an open-label, multicentre, single-arm intervention trial assessed pruritus severity and HRQo… Show more

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