“…Of the fifty-six studies that were reviewed, all were limited by methodological flaws. Thirty (53.6%) studies [11,12,[14][15][16][17]19,20,22,[27][28][29][30][31][32][33][35][36][37]43,46,47,49,[52][53][54]56,58,63,64] did not establish the baseline knowledge, confidence or skills of participants and this is significant in two regards: It does not allow accurate comparison between groups, as differences in baseline knowledge may be responsible for differences in final knowledge; and it does not allow the impact of the intervention in increasing students' performance to be quantified. Three (5.4%) [25,55,57] of the nine studies that reviewed blended learning methods, failed to assess the effectiveness of the e-learning intervention independently of the face-to-face teaching.…”