Impact of educational print materials on knowledge, attitudes, and interest in BRCA1/BRCA2

Schwartz, Marc D.; Benkendorf, Judith; Lerman, Caryn; Isaacs, Claudine; Ryan-Robertson, Anna; Johnson, Lenora

doi:10.1002/1097-0142(20010815)92:4<932::aid-cncr1403>3.0.co;2-q

Cited by 90 publications

(86 citation statements)

References 18 publications

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“…Two studies included a cancer genetics knowledge assessment of Ashkenazi Jewish individuals in their sample. 12,16 Knowledge was higher in the Ashkenazi Jewish group than in other populations, and knowledge increased as a result of receiving general cancer and genetic testing materials. This finding of greater knowledge and greater ability to gain new knowledge is consistent with the cultural emphasis on education and learning among Ashkenazi Jews.…”

Section: Cancer Genetic Knowledge and Interest In Testingmentioning

confidence: 93%

“…Eight [7][8][9][10][11][12][13][14] of the 15 studies identified used the National Institutes of Health National Center for Human Genome Research Cancer Genetics Consortium knowledge scale, 7 an 11-item scale with a true/false response format. Topics included mechanisms of cancer inheritance, frequency of hereditary cancer, meaning of a positive result, and efficacy of cancer screening.…”

Section: Cancer Genetic Knowledge and Interest In Testingmentioning

confidence: 99%

“…11,12,14 Three studies found that higher knowledge before counseling and increases in knowledge were associated with levels of education beyond high school. 11,14,15 Those with graduate education were not examined separately for their level of knowledge, and it is possible that those with graduate education may benefit more from genetic counseling as some concepts may be difficult to comprehend.…”

Section: Cancer Genetic Knowledge and Interest In Testingmentioning

confidence: 99%

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Cancer Genetics Knowledge and Beliefs and Receipt of Results in Ashkenazi Jewish Individuals Receiving Counseling for BRCA1/2 Mutations

et al. 2004

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Background: Genetic counseling for BRCA1 and BRCA2 mutations (mutations associated with increased risk of breast-ovarian cancer) endeavors to communicate information that will help individuals make informed decisions IntroductionGenetic counseling for hereditary breast-ovarian cancer associated with BRCA1/2 mutations represents a specific area for the communication of complex cancer genetic information to assist individuals in making informed decisions about genetic testing. Our study focused on knowledge of and beliefs about breast-ovarian cancer genetics from before to after counseling on specific topics: personal behavior, mechanisms of cancer inheritance, meaning of a positive result, practitioner knowledge, frequency of inherited cancer, and meaning of a negative result. These topic areas have been identified as key to genetic counseling for hereditary breast-ovarian cancer. We located no studies that reported changes in knowledge in key topic areas from before to after counseling and the receipt of results in the Ashkenazi Jewish population at increased risk for having a mutation. Therefore, the goals of this paper are to examine the knowledge of and beliefs about cancer genetics both before and after counseling and the relationship of knowledge and beliefs to receipt of results in the Ashkenazi Jewish population at increased risk for carrying BRCA1/2 mutations. Risks Associated With BRCA1/2 MutationsWomen carrying mutations in BRCA1/2 have up to an 85% risk of breast cancer and up to a 60% risk of ovarian cancer by age 70. 1,2 For men with the BRCA2 gene mutation, the risk of breast cancer is also increased above population rates. 3 In the Ashkenazi Jewish population, the frequency of three BRCA1 and BRCA2 mutations (the Ashkenazi Jewish panel) is approximately 2.6%, 4 while the general population frequency is approximately 0.1%. 5 The presence of risk factors, such as a personal and/or family history of breast or ovarian cancer and multiple generations affected, increases the risk of having a mutation. 2,6 Hence, these mutations occur at a higher frequency in the Ashkenazi Jewish population than in the general population and represent a significant health threat due to their association with cancer.

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Section: Cancer Genetic Knowledge and Interest In Testingmentioning

confidence: 93%

Section: Cancer Genetic Knowledge and Interest In Testingmentioning

confidence: 99%

Section: Cancer Genetic Knowledge and Interest In Testingmentioning

confidence: 99%

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Cancer Genetics Knowledge and Beliefs and Receipt of Results in Ashkenazi Jewish Individuals Receiving Counseling for BRCA1/2 Mutations

et al. 2004

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“…Finally, another US-based group has developed several decision support booklets for women at increased risk for breast/ovarian cancer, including one designed specifically for women with Ashkenazi Jewish heritage [10] and another decision aid for known BRCA1/2 mutation carriers considering their risk management options [11]. Each of these studies has reported positive outcomes from decision aid use, including improved knowledge [10,12] and reduced decisional conflict in women who were initially undecided about the risk management strategies they wanted to adopt [11].…”

Section: A Decision Aid For Women Considering Genetic Testingmentioning

confidence: 99%

A randomized trial of a breast/ovarian cancer genetic testing decision aid used as a communication aid during genetic counseling

Wakefield

Meiser²,

Homewood

et al. 2008

Psycho-Oncology

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Objectives: To evaluate the impact of a decision aid for women considering genetic testing for breast/ovarian cancer risk given during genetic counseling.Methods: One hundred and forty-eight women were randomized to receive the decision aid or a control pamphlet at the beginning of their first consultation with a genetic counselor. When the patient received the decision aid, it was used to complement consultation discussions about genetic testing. One hundred and ten (74.3%) women completed the first questionnaire designed to elicit information about women's levels of decisional conflict and knowledge about genetic testing. Of these, 105 (70.9%) completed a second questionnaire to assess longer-term outcomes, 6 months postconsultation.Results: Results showed that women who received the decision aid felt more informed about genetic testing (w 2 (1) 5 8.69; P 5 0.003), had clearer values (w 2 (1) 5 6.90; P 5 0.009) and had higher knowledge levels (w 2 (2) 5 6.49; P 5 0.039) than women who received the control pamphlet.Conclusions: The developed decision aid improved patient outcomes better than a control pamphlet when implemented during genetic counseling and given to the patient to take home.

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“…18 Various interventions aimed at increasing patient knowledge have been shown to be effective. [19][20][21][22][23][24][25] That said, there are few educational interventions focusing on hereditary breast cancer that target physicians or trainees. 26 Here, we report an evaluation of an interactive web-based genetics curriculum for PCPs using announced standardized patient (SP) visits.…”

Section: Introductionmentioning

confidence: 99%

Impact of a Randomized Controlled Educational Trial to Improve Physician Practice Behaviors Around Screening for Inherited Breast Cancer

et al. 2014

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BACKGROUND: Many primary care physicians (PCPs) are ill-equipped to provide screening and counseling for inherited breast cancer. OBJECTIVE: To evaluate the outcomes of an interactive web-based genetics curriculum versus text curriculum for primary care physicians. DESIGN: Randomized two-group design. PARTICIPANTS: 121 California and Pennsylvania community physicians. INTERVENTION: Web-based interactive genetics curriculum, evaluated against a control group of physicians who studied genetics review articles. After education, physicians interacted with an announced standardized patient (SP) at risk for inherited breast cancer. MAIN MEASURES: Transcripts of visit discussions were coded for presence or absence of 69 topics relevant to inherited breast cancer. KEY RESULTS: Across all physicians, history-taking, discussions of test result implications, and exploration o f e t h i c a l a n d l e g a l i s s u e s w e r e i n c o m p l e t e . Approximately half of physicians offered a genetic counseling referral (54.6 %), and fewer (43.8 %) recommended testing. Intervention physicians were more likely than controls to explore genetic counseling benefits (78.3 % versus 60.7 %, P= 0.048), encourage genetic counseling before testing (38.3 % versus 21.3 %, P= 0.048), ask about a family history of prostate cancer (25.0 % versus 6.6 %, P= 0.006), and report that a positive result indicated an increased risk of prostate cancer for male relatives (20.0 % versus 1.6 %, P= 0.001). Intervention-group physicians were less likely than controls to ask about Ashkenazi heritage (13.3 % versus 34.4 %, P= 0.01) or to reply that they would get tested when asked, "What would you do?" (33.3 % versus 54.1 %, P= 0.03). CONCLUSIONS: Physicians infrequently performed key counseling behaviors, and this was true regardless of whether they had completed the web-based interactive training or read clinical reviews.

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Impact of educational print materials on knowledge, attitudes, and interest in BRCA1/BRCA2

Cited by 90 publications

References 18 publications

Cancer Genetics Knowledge and Beliefs and Receipt of Results in Ashkenazi Jewish Individuals Receiving Counseling for BRCA1/2 Mutations

Cancer Genetics Knowledge and Beliefs and Receipt of Results in Ashkenazi Jewish Individuals Receiving Counseling for BRCA1/2 Mutations

A randomized trial of a breast/ovarian cancer genetic testing decision aid used as a communication aid during genetic counseling

Impact of a Randomized Controlled Educational Trial to Improve Physician Practice Behaviors Around Screening for Inherited Breast Cancer

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