Electrically assisted bicycles (e-bikes) have become increasingly popular and may facilitate active commuting but this comes at the price of safety since e-bikers have a higher risk of traffic accident than conventional cyclists (Haufe et al. 2022). However, the availability of electric energy on-board allows the emergence of active safety systems like antilock braking systems (ABS) that could help reducing the accident rate in the same way it was observed in the last decades for cars and motorcycles (Maier, 2018). ABS is a mechatronic device involving multi-domain expertise (electronics, mechanics, software) and conflicting objectives (cost, performance, perceived quality, safety of operation, safety of testing). This makes a model-based system engineering (MBSE) methodology the best suited approach to develop such a device. In the MBSE context, simulation models are deployed all along the development cycle, from requirements down to testing phases (both verification and validation).