The study appraised the power supply and industrialization in Enugu State, Nigeria. The specific objectives of the study were to: examine the effect of power supply on the operational costs of industries, determine the effect of power supply on the productivity of industries and examine the effect of power supply on the competitiveness of industries in Enugu State, Nigeria. This study adopted a descriptive survey research design. The study employed secondary and primary sources of data. The population of the study was 2,299. Taro Yamani formula was used to determine the sample size of 341. The collected data was analyzed through the use of mean score. The Chi-square- test analysis technique was applied in testing the hypotheses. The findings revealed that Power supply has a significant negative effect on operational costs of industries in Enugu State, Nigeria (this is where (2cal = 357.230, p = 0.000), that Power supply has a significant negative effect on the productivity of industries in Enugu State, Nigeria (this is where (2cal = 258.945, p = 0.000) and that power supply had a significant negative effect on competitiveness of industries in Enugu State, Nigeria (this is where (2cal = 258.945, p = 0.000),. The study recommended that Government should invest in robust power infrastructure, incentivize renewable energy adoption, while firms should explore energy-efficient technologies, engage in cost-sharing initiatives, and invest in backup systems for uninterrupted production.