Impact of electrode tip shape on catheter performance in cardiac radiofrequency ablation

Petras, Argyrios; Weidmann, Zoraida Moreno; Ferrero, Marina Echeverría; Leoni, Massimiliano de; Guerra, José M.; Gerardo-Giorda, Luca

doi:10.1016/j.hroo.2022.07.014

Cited by 5 publications

(1 citation statement)

References 21 publications

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“…We have a fixed contact surface, so we simply impose the displacement due to contact as a Dirichlet boundary condition. This is a reasonable approximation for a cylindrical tip electrode (Petras et al 2022).…”

Section: B3 Catheter Movementmentioning

confidence: 88%

Calibration of a three-state cell death model for cardiomyocytes and its application in radiofrequency ablation

et al. 2023

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Objective. Thermal cellular injury follows complex dynamics and subcellular processes can heal the inflicted damage if insufficient heat is administered during the procedure. This work aims to the identification of irreversible cardiac tissue damage for predicting the success of thermal treatments.Approach. Several approaches exist in the literature, but they are unable to capture the healing process and the variable energy absorption rate that several cells display. Moreover, none of the existing models is calibrated for cardiomyocytes. We consider a three-state cell death model capable of capturing the reversible damage of a cell, we modify it to include a variable energy absorption rate and we calibrate it for cardiac myocytes.Main results. We show how the thermal damage predicted by the model response is in accordance with available data in the literature on myocytes for different temperature distributions. When coupled with a computational model of radiofrequency catheter ablation, the model predicts lesions in agreement with experimental measurements. We also present additional experiments (repeated ablations and catheter movement) to further illustrate the potential of the model.Significance. We calibrated a three-state cell death model to provide physiological results for cardiac myocytes. The model can be coupled with ablation models and reliably predict lesion sizes comparable to experimental measurements. Such approach is robust for repeated ablations and dynamic catheter-cardiac wall interaction, and allows for tissue remodeling in the predicted damaged area, leading to more accurate in-silico predictions of ablation outcomes.

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Section: B3 Catheter Movementmentioning

confidence: 88%

Calibration of a three-state cell death model for cardiomyocytes and its application in radiofrequency ablation

et al. 2023

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Impact of Catheter Orientation on Cardiac Radiofrequency Ablation

Leoni,

Petras,

Weidmann

et al. 2024

Lecture Notes in Computer Science

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The benefits of ablation using TactiFlex compared with TactiCath in an ex vivo model: a face-to-face experimental comparison study

Odake,

Tokuyama,

Aonuma

et al. 2024

J Interv Card Electrophysiol

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Background TactiFlex is a next-generation catheter that is being used increasingly in ablation-treatment strategies. The purpose of this study was to investigate the differences in ablation lesions when the ablation power, time, and perfusion flow are varied with TactiFlex and TactiCath catheters. Methods The TactiFlex and TactiCath catheters were contacted perpendicularly/obliquely/parallel to the swine myocardium at varying powers (30, 40, and 50 W), time points (10, 15, 20, 25, 30, and 40 s), and forces (5, 10, 15, 20, and 30 g); the depth, width, and area of each lesion were measured, and the number of steam pops that occurred was counted. Results A total of 672 (336 lesions for each catheter) radiofrequency (RF) energy applications were delivered and 648 lesions were analyzed, excluding steam pops. The surface area and volume increased significantly with an increasing contact force for the TactiCath. The TactiCath lesions were significantly deeper than those for TactiFlex in most groups with the same power and seconds. The surface area was significantly larger when the catheters were contacted obliquely/parallel to the myocardium than perpendicularly using TactiCath, whereas the difference was less significant in the case of TactiFlex. In a 10-g contact force ablation experiment, TactiFlex did not cause pops, but TactiCath caused pops in 9.8% of cases. Conclusion The TactiFlex lesions were shallower than those of TactiCath. However, TactiFlex catheters reduced the steam pops during RF applications. Those data should help clinicians understand the characteristics of the catheters and develop adequate strategies. Graphical abstract

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Impact of electrode tip shape on catheter performance in cardiac radiofrequency ablation

Cited by 5 publications

References 21 publications

Calibration of a three-state cell death model for cardiomyocytes and its application in radiofrequency ablation

Calibration of a three-state cell death model for cardiomyocytes and its application in radiofrequency ablation

Impact of Catheter Orientation on Cardiac Radiofrequency Ablation

The benefits of ablation using TactiFlex compared with TactiCath in an ex vivo model: a face-to-face experimental comparison study

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