“…Although most teens do not escalate from trying drugs to developing addictive behaviors, even experimenting with substances is a problem. Namely, substance misuse can develop into a pattern of risky behavior including intoxicated driving, unsafe sex, injecting, and violent behavior [ 2 , 3 , 4 ] Therefore, even when adolescents do not develop symptoms of dependence (i.e., repeated substance misuse), even the rare usage of substances can pose a serious health-related risks and lead to socially dangerous behavior, with problems including family problems, failure in school (i.e., educational failure), altered interest in everyday healthy activities (i.e., proper eating, physical exercise), chemsex, mental health problems, impaired memory (i.e., problems with learning), risky sexual behavior with consequent increased risk of contracting infectious diseases (i.e., hepatitis C, HIV), etc. [ 5 , 6 ].…”