Impact of ethanol addition on the solubility of various soybean isoflavones in supercritical carbon dioxide and the effect of glycoside chain in isoflavones

Solubility of daidzin in different organic solvents and (ethyl alcohol+water) mixed solvents

“…In order to obtain a high separation efficiency and drug design of daidzin, a knowledge of (solid + liquid) phase equilibrium for daidzin in various solvents is required [3][4]. The solubility of daidzein was reported in the literautre [5][6][7], but only measured in supercritical carbon dioxide [8]. To our knowledge, the solubility of daidzin was not studied systematically in other solvents.…”

Recent Advances on Soybean Isoflavone Extraction and Enzymatic Modification of Soybean Oil

“…G LW : volume fraction of water in microemulsion-based organogel phase, referred from [60] (% v/v microemulsion-based organogel phase) Log P: hydrophobicity index by Laane et al [34]. P was defined by partition equilibrium (-) M: molar fraction of ethanol in SCCO 2 , referred from [33] α: the power term on the molar fraction of ethanol M, presented by Eq. (1), referred from [33].…”

“…P was defined by partition equilibrium (-) M: molar fraction of ethanol in SCCO 2 , referred from [33] α: the power term on the molar fraction of ethanol M, presented by Eq. (1), referred from [33]. It is summarized in Table 3 (-)…”

“…The effect of the entrainer on solubility is discussed with the hydrophobicity of guest components evaluated from their molecular structure. The thermodynamic relationship between the solubility and the parameter indicated a non-ideal state in SCCO 2 [33].…”