Impact of Feeding on Olive Oil with Thyme on Health Status of First Generation of Rat

Abstract

This study aimed to evaluate the effect of feeding rats on virgin olive oil (VOO) and extra virgin olive oil (EVOO) with or without thyme powder on health status of their first generation. Outcome of pregnancy in each group (pregnant and lactating rats fed on olive oils and thyme which randomly divided into 15 groups) were divided into 2 subgroups (male and female) and feeding a month later (till 8 weeks aged). The babies were weighted, blood was collected and scarified. Organs were removed and weighted. Biochemical assays and bone measurements were evaluated. Generally, the groups fed on VOO had a high number of babies, a low body weight and high of liver weight compared to groups fed on EVOO. Total cholesterol (TC), LDL-C and risk factor of male fed on olive oils (100%) had higher values than groups fed on olive oils (50%). Female groups showed observed that, which groups fed on olive oils (100%) had higher of TC, LDL-C and risk factor than groups fed on (50%). Creatinine and urea were increased in male rats fed on olive oils while decreased in the female rats compared to control group. Male groups fed on VOO and thyme were higher of AST, ALT and ALP than groups fed on EVOO. Concerning female babies, there are a high differences between groups. In groups (male and female) were high levels of Ca and P content of bone were observed in rats fed on VOO and thyme leaves powder compared to groups fed on EVOO and thyme powder diets. In conclusion, the feeding on olive oils (VOO and EVOO) with or without thyme leaves powder diets caused to increasing of fertility, improved lipid profile and increasing Ca and P of bone contents.

The ameliorating effect of the combined extract from GreekThymus vulgarisand bee's honey on the hydrocortisone-induced osteoporosis in rat bone cellsviamodulating the bone turnover, oxidative stress, and inflammation

“…7 Therefore, the treatment of the damaged bone cells with these extracts led to the elevation of P and hydroxyapatite levels as compared with the HC-treated cells. These findings are in accordance with the previous studies that were examined the Egyptian TV 49 and BH. 50 Zn is another essential element in the studied extracts; its anti-osteoporotic effect can be supported by an elevation in the bone mineralization and reduce the osteoclast resorption activities.…”