Impact of Glutathione Peroxidase Activity (Gpx) as Oxidative-Stress Marker and Its Role on Inflammation With Osteoarthritis Patients.

Hatai, Beauty; Ganguly, Apurba; Bandopadhyay, Sandip; Banerjee, SudipK; Hatai, Jubilee

doi:10.21474/ijar01/5183

Cited by 1 publication

(1 citation statement)

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“…4.1.6. Abelmoschus esculentus on Glutathione and Glutathione Peroxidase GSH is a group of enzymes that protect the body from oxidative stress by reducing lipid hydroperoxides and free hydrogen peroxide [124,125]. The general overview of the effect of Abelmoschus esculentus on markers of GPx and GSH is outlined in Table 2.…”

Section: Stz-induced Diabetes In Malementioning

confidence: 99%

Comprehensive Overview of the Effects of Amaranthus and Abelmoschus esculentus on Markers of Oxidative Stress in Diabetes Mellitus

Phoswa,

Mokgalaboni

2023

Life

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The use of medicinal plants in the management of diabetes mellitus (DM) is extensively reported. However, there is still very limited information on the role of these plants as markers of oxidative stress in DM. This current review evaluated the effect of Amaranthus spinosus, Amaranthus hybridus, and Abelmoschus esculentus on markers of oxidative stress in rodent models of DM. Current findings indicate that these plants have the potential to reduce prominent markers of oxidative stress, such as serum malondialdehyde and thiobarbituric acid-reactive substances, while increasing enzymes that act as antioxidants, such as superoxide dismutase, catalase, glutathione, and glutathione peroxidase. This may reduce reactive oxygen species and further ameliorate oxidative stress in DM. Although the potential benefits of these plants are acknowledged in rodent models, there is still a lack of evidence showing their efficacy against oxidative stress in diabetic patients. Therefore, we recommend future clinical studies in DM populations, particularly in Africa, to evaluate the potential effects of these plants. Such studies would contribute to enhancing our understanding of the significance of incorporating these plants into dietary practices for the prevention and management of DM.

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Section: Stz-induced Diabetes In Malementioning

confidence: 99%