Impact of grape pomace flour (GPF) on immunity and immune-antioxidant-anti-inflammatory genes expression in Labeo rohita against Flavobacterium columnaris

Harikrishnan, Ramasamy; Devi, Gunapathy; Doan, Hien Van; Balasundaram, Chellam; Esteban, María Ángeles; Abdel‐Tawwab, Mohsen

doi:10.1016/j.fsi.2021.01.011

Cited by 35 publications

(15 citation statements)

References 89 publications

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“…A. vulgaris showed dose-dependent antiviral and antibacterial properties [ 20 , 21 ]. Moreover, several feed additives revealed significant improvements in fish against F. columnaris infection [ 79 , 80 ].…”

Section: Discussionmentioning

confidence: 99%

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

et al. 2022

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The current perspective is a pioneering trial to assess the efficacy of the dietary supplementation of Alchemilla vulgaris powder (AVP) in the diet of Nile tilapia (Oreochromis niloticus) on growth performance, blood picture, hepatic and renal biomarkers, immune status, and serum and tissue antioxidant capacity and to investigate the resistance against Flavobacterium columnare challenge. Fish (n = 360) were distributed into six groups (three replicates each) and received increasing AVP supplementation levels (0, 2, 4, 6, 8, and 10 g kg−1) for 60 days. Furthermore, fish were exposed to the bacterial challenge of a virulent F. columnare strain and maintained under observation for 12 days. During the observation period, clinical signs and the cumulative mortality percentage were recorded. The results demonstrated that the growth performance, feed conversion ratio, and hematological profile were noticeably enhanced in the AVP-supplemented groups compared to the control. The most promising results of weight gain and feed conversion ratio were recorded in the groups with 6, 8, and 10 g AVP kg−1 diets in a linear regression trend. The levels of hepatorenal function indicators were maintained in a healthy range in the different dietary AVP-supplemented groups. In a dose-dependent manner, fish fed AVP dietary supplements displayed significant augmented serum levels of innate immune indicators (lysozyme, nitric oxide, and complement 3) and antioxidant biomarkers (Catalase (CAT), superoxide dismutase (SOD), total antioxidant (TAC), and reduced glutathione (GSH) with a marked decrease in myeloperoxidase (MPO) and malondialdehyde (MDA) levels). Likewise, hepatic CAT and SOD activities were significantly improved, and the opposite trend was recorded with hepatic MDA. The highest AVP-supplemented dose (10 g/kg) recorded the highest immune-antioxidant status. Based on the study findings, we highlight the efficacy of AVP as a nutraceutical dietary supplementation for aquaculture to enhance growth, physiological performance, and immune-antioxidant status and as a natural economic antibacterial agent in O. niloticus for sustaining aquaculture. It could be concluded that the dietary supplementation of 10 g AVP/kg enhanced O. niloticus growth, physiological performance, immune-antioxidant status, and resistance against F. columnare.

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Section: Discussionmentioning

confidence: 99%

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

et al. 2022

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“…The chemical composition of grape pomace of white and red varieties is variegated; it includes components of various nature -polyphenols, polysaccharides, nitrogenous matters, vitamins, major and minor nutrients; and lipids contained in seeds. Their sustainable use will make it possible to produce various food products, including with functional properties [1,2,3,4,5], and antiradical and antioxidant activity [6,7,8,9, 10] -viz., polyphenol concentrates, grape oil, soft drinks, dietary fibres, etc. [11,12,13,14,15].…”

Section: Introductionmentioning

confidence: 99%

Study of phenolic compounds and lipids of grape pomace

et al. 2021

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The article is devoted to the research of the makeup of phenolic compounds and fatty acids of grape pomace. The phenolic compounds were identified in skin and seed extracts and in extracts of skin-and-seed mixtures; the fatty acids – in grape oil generated by direct pressing. It was established that anthocyanins were present mainly in the skins. Low concentrations of ten components of the anthocyanin complex were identified in the Saperavi seeds. Maximum amounts of anthocyanins were found in the Saperavi skins. The concentration of quercetin distinguished by a PP-vitamin activity was by 1.5 to 2.0 times higher in the skin-andseed mixtures, especially of Roesler grapes, than in the skin itself. Maximum amounts of flavan-3-ols, hydroxy-cinnamic and hydroxybenzoic acids and oligomeric procyanidins, as well as the highest antioxidant activity were observed in the skin-and-seed mixture. The highest value of the correlation factor was observed in cases of interaction of antioxidant activity and concentration of procyanidins (r = 0.83), antioxidant activity and concentration of anthocyanins (r = 0.78), and antioxidant activity and concentration of flavan-3-ols (r = 0.75). Among the flavan-3-ols, it was (+)-D-Catechin that prevailed in grape seeds, with its concentration in the Pinot Noir extract (OAO APF Fanagoria) reaching 468 mg/dm3. Maximum concentration of Epigallocatechin-gallate was observed in the Saperavi and Pinot Noir seeds. As regards the concentration of hydroxy-cinnamic acids in the seeds, n-coumaric acid (Ancellotta, Saperavi) stood apart among the others; gallic acid (Saperavi, Ancellotta) came forward among the hydroxy-benzoic acids. In the reviewed samples of grape seeds, procyanidins of groups В1 , В2 and В3 distinguished by high antioxidant activity prevailed. Prevalence of linoleic and oleic acids was established for grape oil extracted from the seeds of such red grape varieties as Cabernet Sauvignon, Pinot Noir and Saperavi. Maximum concentrations of oleic acid were found in the Pinot Noir and Riesling seeds. Palmitic and stearic acids were also available in rather high concentrations in the grape oil.

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“…Phytobiotic application improves nutrient availability and digestibility, contributing to enhanced feed conversion and protein synthesis [7]. Various phytobiotics like oregano essential oil [40], curcumin [21], grape pomace flour (GPF) [34], and savory (Satureja hortensis) essential oil [38] are easily applicable in carp farming as shown in Table 2. Nevertheless, these phytobiotics are only useful when the aquaculture species nutritional requirements are fulfilled.…”

Section: The Role Of Phytobiotics In Promoting Carp Feed Utilization ...mentioning

confidence: 99%

“…Moreover, some phytobiotics are inexpensive in the market, making them accessible to most carp farmers. Examples of phytobiotics that promote antioxidant activities in carps are Chlorella [18], garlic [43], ulvan [44], and grape pomace flour (GPF) [34]. Nonetheless, inadequate resources and the high processing cost of the current technology are limitations to the phytobiotic application in carp farming [3,5].…”

Section: The Role Of Phytobiotics In Enhancing Carp Antioxidant Activ...mentioning

confidence: 99%

“…Generally, phytobiotics with high antioxidant properties can stimulate the fish immune system [52]. Some phytobiotics are low cost and easy to access such as garlic [43], grape pomace flour (GPF) [34], ulvan [44], and turmeric powder [53], which can be used to boost carps' immune response and increase fish production as shown in Table 4. However, certain plant-based products must be processed before they can be used as an aquaculture feed additive, such as Psidium guajava leaf [54] and dried lemon (Citrus limon) peel [48].…”

Section: The Role Of Phytobiotics In Activating An Innate Immunementioning

confidence: 99%

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Recent Advances of Phytobiotic Utilization in Carp Farming: A Review

Kari

Wee

Hamid

et al. 2022

Aquaculture Nutrition

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Carp farming is a popular aquaculture activity that provides affordable protein sources and job opportunities to many people worldwide. As carp farming intensifies, farmers face major issues such as rising feed costs and excessive antibiotic usage. Thus, there is an urgent need to explore alternative resources to ensure the sustainability of the carp farming industry. One of the most promising resources is phytobiotics that possess various properties beneficial for carp production. Furthermore, most phytobiotics are derived from agricultural waste that is abundant and cheap, but some phytobiotics are produced commercially and available in the market. The main topics of this review are highlighted sources, characteristics of phytobiotics, and the usefulness of phytobiotics in improving growth performance, feed utilization efficiency, antioxidant activity, and health of carps against diseases. Furthermore, in this review, recent methods of administration of phytobiotics such as through feeding, bathing, and intraperitoneal injection in carp farming are also discussed and summarised.

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Impact of grape pomace flour (GPF) on immunity and immune-antioxidant-anti-inflammatory genes expression in Labeo rohita against Flavobacterium columnaris

Cited by 35 publications

References 89 publications

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

Study of phenolic compounds and lipids of grape pomace

Recent Advances of Phytobiotic Utilization in Carp Farming: A Review

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