2000
DOI: 10.1053/jinf.2000.0672
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Impact of Highly Active Antiretroviral Therapy in HIV-positive Patients with Cardiac Involvement

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Cited by 170 publications
(103 citation statements)
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“…The rate of progression from left ventricular dysfunction to heart failure can be considerably slowed by HAART therapy [15]. Although there is no conclusive evidence that HAART reverses cardiomyopathy, it appears, however, that by preventing profound immunosuppression and the development of AIDS, heart muscle remain healthier [41][42][43]. Therefore, a major focus on prevention and treatment strategies for HIV-related heart disease in developing countries should include, among others, an aggressive campaign to get universal access to HAART.…”
Section: Discussionmentioning
confidence: 99%
“…The rate of progression from left ventricular dysfunction to heart failure can be considerably slowed by HAART therapy [15]. Although there is no conclusive evidence that HAART reverses cardiomyopathy, it appears, however, that by preventing profound immunosuppression and the development of AIDS, heart muscle remain healthier [41][42][43]. Therefore, a major focus on prevention and treatment strategies for HIV-related heart disease in developing countries should include, among others, an aggressive campaign to get universal access to HAART.…”
Section: Discussionmentioning
confidence: 99%
“…One Italian study reported an almost 7-fold reduction of the prevalence of HIV-associated myocarditis from the pre-HAART era [Pugliese et al, 2000]. In that study there is no conclusive evidence that HAART reverses cardiomyopathy, but it does appear that by preventing profound immunosuppression and the development of AIDS, heart muscle remains healthier [Pugliese et al, 2000].…”
Section: Treatmentmentioning
confidence: 99%
“…By preventing opportunistic infections and reducing the incidence of myocarditis, HAART regimens have reduced the prevalence of HIV-associated myocarditis to about 30% [Barbaro 2005]. One Italian study reported an almost 7-fold reduction of the prevalence of HIV-associated myocarditis from the pre-HAART era [Pugliese et al, 2000]. In that study there is no conclusive evidence that HAART reverses cardiomyopathy, but it does appear that by preventing profound immunosuppression and the development of AIDS, heart muscle remains healthier [Pugliese et al, 2000].…”
Section: Treatmentmentioning
confidence: 99%
“…The introduction of highly active antiretroviral therapy (HAART) has significantly reduced the incidence of HIV related-myocarditis. On the other hand, in developing countries where the supply of HAART is limited, researchers have observed increase in prevalence of HIV associated cardiomyopathy (Pugliese et al, 2000).…”
Section: Etiologymentioning
confidence: 99%