Impact of HIV infection on mortality in young men in a London health authority.

Aldous, John; Hickman, Matthew; Ellam, Anthony; Gazzard, Brian; Hargreaves, Shila Minari

doi:10.1136/bmj.305.6847.219

Cited by 11 publications

(6 citation statements)

References 9 publications

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“…Compared to other developed countries, a similar impact has only been described in those hit hardest by the AIDS epidemic, 3,12 and in certain especially affected cities or regions. [13][14][15] The order in which causes are ranked is heavily influenced by the categories established for comparison. In our analysis, the criterion used had the effect of diminishing the relative importance of HIV/AIDS.…”

Section: Discussionmentioning

confidence: 99%

“…The important impact exerted by HIV/AIDS on mortality among young Spanish women is remarkable when compared to that described for other developed countries, which report noteworthy results for men alone. [13][14][15]20,21 As with other countries, 12,15 wide geographical differences have been described for the distribution of HIV/AIDS mortality in Spain. 22 Previous papers have reported the great impact of AIDS on mortality in some of the hardest-hit cities and regions, i.e.…”

Section: Discussionmentioning

confidence: 99%

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Impact of human immunodeficiency virus infection on mortality among young men and women in Spain

Castilla

Aragón²,

Gutiérrez³

et al. 1997

International Journal of Epidemiology

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A, Llácer A, Belza M J, Ruiz C, Pérez de la Paz J and Noguer I. Impact of human immunodeficiency virus infection on mortality among young men and women in Spain. International Journal of Epidemiology 1997; 26: 1346-1351. Background. This paper describes the impact of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) mortality among young adults in Spain with specific reference to other causes of death. Methods. Based on death registration data for the period 1980-1993, HIV/AIDS was compared against all other causes of death by gender, using specific rates in the 25-44 age group and standardized rates for potential years of life lost (PYLL). Results. In 1993, HIV/AIDS was the leading cause of death among men aged 25-44 years (21.8% of all deaths) and the second leading cause of death among women (14.9%), exceeded only by cancer. Since 1982, the trend in the overall standardized mortality rate for men in the 25-44 age group has been reversed, showing a progressive increase. Similarly, since 1984 there has been a halt in the decline in female mortality. For both sexes, maintenance of these trends in mortality was largely ascribable to the effect of HIV/AIDS deaths which registered a marked rise, a rise far sharper than that witnessed for variations in all other causes studied. In 1993, the adjusted PYLL rate for HIV/AIDS for ages 1-70 rose to 615 per 100 000 population in men and 156 in women. These values accounted for 9.2% and 5.8% of PYLL for all causes, thereby ranking HIV/AIDS behind motor vehicle accidents as the second leading cause of premature death in men, and behind motor vehicle accidents and breast cancer as the third leading cause in women. For both sexes, the rise in the PYLL rate for HIV/AIDS from 1992 to 1993 proved far greater than that for all other causes of death. Conclusion. In Spain, HIV/AIDS has become the leading cause of death among young adults and is counteracting improvements in mortality due to other causes. It should therefore be regarded as a priority public health problem.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Impact of human immunodeficiency virus infection on mortality among young men and women in Spain

Castilla

Aragón²,

Gutiérrez³

et al. 1997

International Journal of Epidemiology

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“…The insidious progress of HIV is perhaps underscored by examination of mortality figures. In one London health authority, HIV infection is now the main cause of death in male residents aged 1544, and the third commonest cause of death in those aged 15-64 (Aldous et al, 1992). Although considerable efforts have been made to develop medical treatments that will delay the onset of AIDS in HIV positive individuals, results have been disappointing.…”

Section: Strategies For Hiv Sexual Risk Reduction Frank Tallismentioning

confidence: 99%

Cognitive behavioural strategies for HIV sexual risk reduction

Tallis¹

1995

Clin Psychology and Psychoth

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Unprotected sexual intercourse is the principal means of transmission for HIV; the virus associated with AIDS. In the absence of effective medical treatment, the modification of sexual behaviour remains the most important method of containment. A cognitive behavioural model of risky sexual behaviour is described. Intervention strategies suggested by the model are discussed in some detail. These include a novel procedure that potentiates state dependent memory effects. Finally, three cases are presented in order to underscore key points.

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“…8 An earlier study also suggested that HIV infection was one of the leading causes of death in young men in a small area of London. 9 One diYculty is that HIV related deaths are partially hidden among routine mortality statistics, as they can be classified under a number of diVerent ICD codes often without mentioning underlying HIV infection. 10 11 It has been observed that male mortality in inner London has not been falling as fast as in other parts of the country, and some of this may be related to the eVects of HIV.…”

Section: Introductionmentioning

confidence: 99%

Impact of HIV on adult (15-54) mortality in London: 1979-96

Hickman

Bardsley

Angelis

et al. 1999

Sexually Transmitted Infections

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Objective:To describe the impact of HIV on mortality in men and women aged 15-54 in London. Design: Combination of routine mortality statistics with reports of AIDS deaths adjusted for underreporting and change in address from time of report to time of death. Calculation of standardised mortality ratios (SMRs) for males including and excluding HIV comparing inner London and outer London with the rest of England and Wales. Methods: Comparison of trends in all cause mortality and SMRs in males over time. Comparison of trends in HIV related deaths with other main causes of deaths in males and females in London. Results: Age standardised rates for the rest of England and Wales showed a continual decline from 1979 to 1996 but rates in inner London males (ages 15-54) stopped declining around 1984-5 leading to a considerable increase in the SMR for inner London from 127 for 1985-7 to 171 for 1994-6. SMRs excluding HIV related deaths for inner London, however, showed no significant change over this time. There was a fall in HIV related mortality in 1996, though HIV was still the leading cause of death in males and second leading cause of death in females in inner London, and the fourth commonest cause of death in males in outer London. Conclusion: These data are the first to indicate the impact of HIV on mortality within a significant population in England and Wales. They show that public health priorities in London are different from the rest of the country. Analyses of trends of all cause mortality in people under 65 may mislead unless they take account of HIV. (Sex Transm Inf 1999;75:385-388)

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Impact of HIV infection on mortality in young men in a London health authority.

Cited by 11 publications

References 9 publications

Impact of human immunodeficiency virus infection on mortality among young men and women in Spain

Impact of human immunodeficiency virus infection on mortality among young men and women in Spain

Cognitive behavioural strategies for HIV sexual risk reduction

Impact of HIV on adult (15-54) mortality in London: 1979-96

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