Impact of HIV on inpatient mortality and complications in stroke in Thailand: a National Database Study

Cumming, Kirsten; Tiamkao, Somsak; Kongbunkiat, Kannikar; Clark, Allan; Bettencourt‐Silva, Joao H.; Sawanyawisuth, Kittisak; Kasemsap, Narongrit; Mamas, Mamas A.; Seeley, Janet; Myint, Phyo Kyaw

doi:10.1017/s095026881600340x

Cited by 13 publications

(12 citation statements)

References 17 publications

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“…Data were acquired from the NHSO, which provides health coverage under the Universal Coverage Scheme (UCS) in Thailand, which has been described in detail elsewhere. 4,5 The UCS covers out-patient, inpatient, and emergency care for citizens in all provinces. In 2017, the UCS covered 73.7% of the 66.19 million Thai citizens.…”

Section: Data Sources and Extractionmentioning

confidence: 99%

The epidemiology of Guillain‐Barré syndrome in Thailand over 13 years (2005‐2017): A nationwide population‐based retrospective cohort study

Kasemsap

Vorasoot

Kongbunkiat

et al. 2021

J Peripheral Nervous Sys

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There have been no published studies examining the epidemiology of Guillain-Barré syndrome (GBS) in large populations in Thailand. This study aimed to explore the incidence, patient characteristics, seasonality, treatments, and outcomes of GBS in Thailand. The National Health Security Office (NHSO) provided data on in-patient admission between fiscal year 2005 and 2017. We selected all patients with a primary diagnosis of GBS. We retrieved data regarding the total population from the Department of Provincial Administration. A total of 4521 patients with GBS were included. The median age was 42 years (IQR 22-56), and 61.5% were male. The incidence rate increased from 0.48 to 0.93 per 100 000 population over the 13 years.The incidence was increased with age and a male-to-female ratio of 1.6:1. There was seasonal variation in the rate of admission for GBS, with significantly more patients admitted in rainy vs summer (IRR 1.94, 95%CI 1.80-2.10, P < .001) and winter vs summer (IRR 1.48, 95%CI 1.36-1.60, P < .001). Treatment with IVIg increased from 4.4% to 29.6% (P < .001), whereas plasmapheresis decreased significantly from 4% to 1.32% (P = .017). The mortality rate was 3.5%. Elderly and young adults had a significantly higher mortality rate when compared to children and teenagers (P < .001 and P = .003). The incidence of GBS in Thailand was steady over 13 years and was greater in rainy and winter season. Treatment with IVIg increased while plasmapheresis decreased. Mortality was higher in elderly patients.

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Section: Data Sources and Extractionmentioning

confidence: 99%

The epidemiology of Guillain‐Barré syndrome in Thailand over 13 years (2005‐2017): A nationwide population‐based retrospective cohort study

Kasemsap

Vorasoot

Kongbunkiat

et al. 2021

J Peripheral Nervous Sys

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“…In a hospital study in Cameroon, men were more likely to be found among PLWH with stroke [ 19 ]. In the literature, there is variability according to sex, with the majority of studies favoring a male preponderance [ 19 - 21 ]. Nevertheless, it is demonstrated that women living with HIV have a higher immune activation in than seronegative women and men [ 22 , 23 ].…”

Section: Discussionmentioning

confidence: 99%

“…PLWH had high proportions of ischemic stroke. In the majority of studies performed, PLWH had more ischemic strokes [ 18 , 20 , 21 , 34 ]. This result is similar to those found in Cameroon, Tanzania, and Malawi [ 15 , 18 , 20 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular risk and stroke mortality in persons living with HIV: a longitudinal study in a hospital in Yaounde

et al. 2021

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Introduction HIV infection is a well-known risk factor for stroke, especially in young adults. In Cameroon, there is a death of data on the outcome of stroke among persons living with HIV (PLWH). This study aimed to assess the cardiovascular risk profile and mortality in PLWH who had a stroke. Methods this was a retrospective cohort study of all PLWH aged ≥18 years admitted for stroke between January 2010 and December 2019 to the Cardiology Unit of the Yaoundé Central Hospital, Cameroon. Cardiovascular risk was estimated using the modified Framingham score, with subsequent dichotomization into low and intermediate/high risk. Mortality was assessed on day 7 during hospitalization (medical records), at one month, and one year by telephone call to a relative. Results a total of 43 PLWH who had a stroke were enrolled. Their mean age was 52.1 (standard deviation 12.9) years, most of them were female (69.8%, n = 30). There were 25 (58.1%) patients on concomitant antiretroviral therapy. The Framingham cardiovascular risk score at admission was low in 29 patients (67.4%) and intermediate to high in 14 patients (32.6%). Ischemic stroke was the most common type of stroke in 36 persons (83.7%). The length of hospital stay was 11.4 (interquartile range 9.2-13.7) days. Mortality at 1 year was 46.5% (n = 20). Conclusion stroke mortality was high in this population of PLWH. Most patients had a low Framingham score, suggesting that this risk estimation tool underestimates cardiovascular risk in PLWH.

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“…Our study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki as reflected in a prior approval by the Ethics Committee in Human Research, Khon Kaen University, Khon Kaen, Thailand. The description of the cohort has also been described previously 13,14 …”

Section: Methodsmentioning

confidence: 99%

Infective endocarditis is associated with worse outcomes in stroke: A Thailand National Database Study

Reid

Barlasm

Mamas

et al. 2020

Int. J. Clin. Pract.

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Impact of HIV on inpatient mortality and complications in stroke in Thailand: a National Database Study

Cited by 13 publications

References 17 publications

The epidemiology of Guillain‐Barré syndrome in Thailand over 13 years (2005‐2017): A nationwide population‐based retrospective cohort study

The epidemiology of Guillain‐Barré syndrome in Thailand over 13 years (2005‐2017): A nationwide population‐based retrospective cohort study

Cardiovascular risk and stroke mortality in persons living with HIV: a longitudinal study in a hospital in Yaounde

Infective endocarditis is associated with worse outcomes in stroke: A Thailand National Database Study

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