Impact of hormonal status on ductal carcinoma in situ of the breast: Outcome and prognostic factors

Tay, Tricia; Ng, Wai Yee; Ong, Kong Wee; Wong, Chow Yin; Tan, Benita Kiat Tee; Yong, Wei Sean; Madhukumar, Preetha; Tan, Veronique Kiak Mien; Lim, Si Ching; Sim, Yirong

doi:10.1111/tbj.13738

Cited by 3 publications

(3 citation statements)

References 28 publications

(40 reference statements)

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“… 86 Another Singaporean study discovered that the 1, 3, and 5 years overall survival (OS) rates were 99.8%, 98.7%, and 97.1%, respectively. 87 …”

Section: Resultsmentioning

confidence: 99%

“…BCS 79,87 Mastectomy 83,87 Chemotherapy, Neo-adjuvant chemotherapy 80 Radiation therapy 87 Hormone therapy, Tamoxifen 80,87 BCS 14,62 Radical or simple mastectomy 14 Radiation therapy 14,62,77 Systemic therapy with cytotoxic drugs 14,62 Hormone therapy, Tamoxifen 14 Immunotherapeutic agents 14…”

Section: Treatmentmentioning

confidence: 99%

“…86 Another Singaporean study discovered that the 1, 3, and 5 years overall survival (OS) rates were 99.8%, 98.7%, and 97.1%, respectively. 87 Between January 2005 and December 2009, 868 women were diagnosed with breast cancer in Malaysia, with an overall survival rate of 43.5%, with Chinese, Indians, and Malays having 5-year survival rates of 48.2%, 47.2%, and 39.7%, respectively. The percentage of survivors decreased as the phases progressed, with Malays (46%) being the most affected, followed by Chinese (36%) and Indians (34%).…”

Section: Survivalmentioning

confidence: 99%

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A Scoping Review on the Status of Female Breast Cancer in Asia with a Special Focus on Nepal

Dhakal¹,

Νούλα²,

Ρούπα³

et al. 2022

BCTT

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This study aimed to provide updated evidence on the status of female breast cancer and cancer treatment facilities in Asia, with a special focus on Nepal. This review used search phrases that included, breast neoplasm or cancer, health status, epidemiology, breast cancer survivors, cancer care facilities, Asia, Nepal. Researchers examined databases from January 2011 to December 2020 (PubMed, PMC, Google Scholar, and the reference lists of included papers). Studies of any design and reviews, were included in the study, except for qualitative studies. The study findings are presented in a narrative synthesis format using Preferred Reporting Items for Systematic Reviews and Meta-analyses Extension for Scoping Reviews. An initial search resulted in 974 papers, and 896 were reviewed after being checked for duplication using the Zotero software. Accordingly, utilizing the inclusion and exclusion criteria, 188 publications were selected, and after review of titles and abstracts, an additional 98 papers were removed for different reasons. Finally, the study looked at 90 female breast cancer papers. Results showed that the number of cases of breast cancer is growing all around the world, including in Asia and Nepal. Age, early menarche, late menopause, nulliparity, positive family history, excessive fat consumption, alcohol, and smoking are all frequent risk factors for breast cancer found in Asian women. Breast self-examination, clinical breast examination, and mammography screening are common methods for detecting breast carcinoma. Chemotherapy, radiation, and modified mastectomy are commonly used options for treatment. The number of breast cancer survivors is growing throughout the world, indicating better clinical care. There is a paucity of survival data in many Asian countries, including Nepal. There is also a scarcity of health workforce specialized in cancer care and treatment, as well as a few health facilities that are available to treat cancer cases in many Asian countries, including Nepal.

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“… 86 Another Singaporean study discovered that the 1, 3, and 5 years overall survival (OS) rates were 99.8%, 98.7%, and 97.1%, respectively. 87 …”

Section: Resultsmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

Section: Survivalmentioning

confidence: 99%

See 1 more Smart Citation

A Scoping Review on the Status of Female Breast Cancer in Asia with a Special Focus on Nepal

Dhakal¹,

Νούλα²,

Ρούπα³

et al. 2022

BCTT

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Recidiva locorregional del cáncer de mama

Colombo¹,

Taoum²,

Rouanet³

2022

EMC - Ginecología-Obstetricia

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Radiological Underestimation of Tumor Size as a Relevant Risk Factor for Positive Margin Rate in Breast-Conserving Therapy of Pure Ductal Carcinoma In Situ (DCIS)

Schultek

Gerber

Reimer

et al. 2022

Cancers

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Background: Radiological underestimation of the actual tumor size is a relevant problem in reaching negative margins in ductal carcinoma in situ (DCIS) associated with microcalcifications in breast-conserving therapy (BCT). The aim of this study is to evaluate whether the radiological underestimation of tumor size has an influence on the histopathological margin status. Methods: Patients who underwent BCT with preoperatively diagnosed pure DCIS were included (pooled analysis of two trials). Multiple factors were analysed regarding radiological underestimation ≥10 mm. Radiological underestimation was defined as mammographic minus histological tumor size in mm. Results: Positive margins occurred in 75 of 189 patients. Radiological underestimation ≥10 mm was an independent influencing factor (OR 5.80; 95%CI 2.55–13.17; p < 0.001). A radiological underestimation was seen in 70 patients. The following parameters were statistically significant associated with underestimation: pleomorphic microcalcifications (OR 3.77; 95%CI 1.27–11.18), clustered distribution patterns (OR 4.26; 95%CI 2.25–8.07), and mammographic tumor sizes ≤20 mm (OR 7.47; 95%CI 3.49–15.99). Only a mammographic tumor size ≤20 mm was an independent risk factor (OR 6.49; 95%CI 2.30–18.26; p < 0.001). Grading, estrogen receptor status, and comedo necrosis did not influence the size estimation. Conclusion: Radiological underestimation is an independent risk factor for positive margins in BCT of DCIS associated with microcalcifications predominantly occurring in mammographic small tumors.

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Impact of hormonal status on ductal carcinoma in situ of the breast: Outcome and prognostic factors

Cited by 3 publications

References 28 publications

A Scoping Review on the Status of Female Breast Cancer in Asia with a Special Focus on Nepal

A Scoping Review on the Status of Female Breast Cancer in Asia with a Special Focus on Nepal

Recidiva locorregional del cáncer de mama

Radiological Underestimation of Tumor Size as a Relevant Risk Factor for Positive Margin Rate in Breast-Conserving Therapy of Pure Ductal Carcinoma In Situ (DCIS)

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