Biopharmaceuticals 2018
DOI: 10.5772/intechopen.78603
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Impact of Immunotherapy in the Treatment of Glioblastoma

Abstract: Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor. Despite the efforts developed in the respective treatment, consisting of maximal surgical resection followed by adjuvant radiotherapy and chemotherapy, the prognosis remains very poor. This may be partly related to the resistance of GBM cells and their infiltrative and invasive nature into the surrounding brain tissue. Therefore, newer and challenging alternative approaches for the treatment have emerged, including i… Show more

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