Impact of Inspired Gas Mixtures on Preoperative Infants With Hypoplastic Left Heart Syndrome During Controlled Ventilation

Tabbutt, Sarah; Ramamoorthy, Chandra; Montenegro, Lisa M.; Durning, Suzanne; Kurth, C. Dean; Steven, James M.; Godinez, Rodolfo I.; Spray, Thomas L.; Wernovsky, Gil; Nicolson, Susan C.

doi:10.1161/hc37t1.094818

Cited by 167 publications

(74 citation statements)

References 22 publications

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“…13 In the only published clinical comparison of hypoxia (17%) and hypercarbia (FiCO 2 2.7%), 10 anaesthetised infants with unoperated HLHS were evaluated in a prospective, randomised, crossover trial. 14 Both manoeuvres similarly decreased Qp:Qs and arterial oxygen saturations. Hypercarbia, but not hypoxia, increased systolic and diastolic blood pressure, and also increased the mixed venous and cerebral oxygen saturations, suggesting improved systemic oxygen delivery.…”

Section: Respiratory Managementmentioning

confidence: 86%

The intensive care of infants with hypoplastic left heart syndrome

Theilen

Shekerdemian²

2005

Archives of Disease in Childhood - Fetal and Neonatal Edition

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Section: Respiratory Managementmentioning

confidence: 86%

The intensive care of infants with hypoplastic left heart syndrome

Theilen

Shekerdemian²

2005

Archives of Disease in Childhood - Fetal and Neonatal Edition

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“…Previously, mechanical ventilation was used for excessive tachypnea and high oxygen saturation, but in current practice, mechanical ventilation is reserved for patients with respiratory insufficiency or failure or low systemic output. 30,31 Spontaneous breathing is preferable, but if necessary, noninvasive ventilatory support can be used to reduce work of breathing and oxygen consumption.…”

Section: Mechanical Ventilationmentioning

confidence: 99%

“…30,31 In current practice, permissive hypercapnea is used and is well tolerated, but inspired carbon dioxide is not used. Finally, noninvasive positive pressure ventilation or invasive positive end-expiratory pressure can be used to achieve lung volumes that exceed functional residual capacity.…”

Section: Mechanical Ventilationmentioning

confidence: 99%

Preoperative Stabilization of Infants With Hypoplastic Left Heart Syndrome Before Stage I Palliation

Donnellan

Justice

2016

Critical Care Nurse

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Hypoplastic left heart syndrome is a severe form of congenital heart disease that results in single-ventricle physiology. Although surgical palliation in infants with this syndrome is widely agreed on in practice, variation occurs in both surgical and medical management. Perinatal factors that affect preoperative management include the subtype of the syndrome and the patient's birth weight, gestational age, and genetic abnormalities. The general aspects of perioperative stabilization and management are monitoring, use of vasoactive infusions, ventilatory support, and nutrition. Management strategies for balancing single-ventricle physiology are aimed at addressing the 3 major causes of desaturation: diminished pulmonary blood flow, low mixed venous oxygen saturation, and pulmonary venous desaturation. (Critical Care Nurse. 2016; 36[1]:52-59)

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“…These approaches have been well reported in the medical literature. [41][42][43][44][45] To optimize patient safety, comprehensive monitoring systems and carefully considered policies and procedures should be in place before utilizing either of these inhaled therapies.…”

Section: Inhaled Medical Gases: More To Breathe Than Oxygenmentioning

confidence: 99%

Neonatal and Pediatric Respiratory Care: What Does the Future Hold?

DiBlasi

Cheifetz

2011

Respir Care

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Neonatal and pediatric respiratory care continues to move forward at a truly impressive pace. Recent technologic advances and an increasing number of randomized clinical trials are leading to improved outcomes for neonates, infants, children, and adolescents with respiratory illness. The goals of this 47th RESPIRATORY CARE Journal Conference were to review pertinent recent advances in neonatal and pediatric respiratory care and, more importantly, to offer thoughts and perspectives for the future of our field. It is important to note that of the prior 46 Journal Conferences, only 2 have been dedicated to neonatal and/or pediatric respiratory care topics. It is our hope that the publication of these proceedings will provide respiratory therapists, physicians, and other members of the clinical care team a foundation on which to ponder the future of neonatal and pediatric respiratory care.

show abstract

Impact of Inspired Gas Mixtures on Preoperative Infants With Hypoplastic Left Heart Syndrome During Controlled Ventilation

Cited by 167 publications

References 22 publications

The intensive care of infants with hypoplastic left heart syndrome

The intensive care of infants with hypoplastic left heart syndrome

Preoperative Stabilization of Infants With Hypoplastic Left Heart Syndrome Before Stage I Palliation

Neonatal and Pediatric Respiratory Care: What Does the Future Hold?

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