Impact of insulin pump therapy on long-term glycemic control in a pediatric Spanish cohort

Real‐world outcomes of insulin pump compared to injection therapy in a population‐based sample of children with type 1 diabetes

“…The strength of this study is that although it is not a RCT, it analyses “real‐world” outcomes of a large population‐based cohort over a longer duration than previously reported. It differs from other pediatric studies which often include only a small number of patients, have a much shorter follow‐up time, and do not include a control group (patients on injection therapy) . Furthermore, data in this study come from a population‐based database with high case ascertainment, and pairs were matched with a random‐sampling algorithm that minimizes a potential selection bias.…”

“…It differs from other pediatric studies which often include only a small number of patients, have a much shorter follow-up time, and do not include a control group (patients on injection therapy). [6][7][8][9][10] Furthermore, data in this study come from a population-based database with high case ascertainment, and pairs were matched with a random-sampling algorithm that minimizes a potential selection bias. There are few pediatric randomized controlled trials comparing patients on pump therapy and patients on injection therapy, and all have a duration of less than 1 year.…”

Continuous Subcutaneous Insulin Infusion Characteristics in Type 1 Diabetes Children and Adolescents in Qatar

“…In our study, CSII efficacy and safety could not be analyzed due to the lack of a control group and missing data. While CSII treatment is well established and has been shown to decrease the HbA1c level compared to MDI [ 18 – 20 ], a recent study does not support a policy of providing an insulin pump to a patient with poor glycemic control until that patient’s level of engagement in self-management has been determined [ 21 ]. Our findings show an average reduction of HbA1c levels of − 1.6% at 1 year after of CSII initiation, with a reduction of − 1.9% achieved in patients using the MiniMed ® 640 G model.…”

Treating with insulin pumps in children under the age of 10 years from diabetes type 1 diagnosis – 3 years follow-up

“…Nie stwierdziliśmy różnicy pomiędzy grupami w wartości HbA1c przy rozpoznaniu. W przeciwieństwie do naszych wyników badacze z Hiszpanii zauważyli, że im gorsze wyrównanie metaboliczne przy podłączeniu pompy insulinowej, tym większy spadek HbA1c [15]. Niemniej jednym ze wskazań do podłączenia pompy insulinowej zgodnie z wytycznymi PTD są trzymające się podwyższone wartości HbA1c>6,5%, ale<9,0%, u pacjenta dobrze wyedukowanego, współpracującego oraz przestrzegającego zasad samokontroli [5].…”