Impact of intensive care on renal function before graft harvest: results of a monocentric study

Blasco, V.; Léone, Marc; Bouvenot, Julien; Geißler, A.; Albanèse, Jacques; Martin, Claude

doi:10.1186/cc6120

Cited by 25 publications

(23 citation statements)

References 24 publications

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“…Appropriate management of DI, restoration of adequate intravascular volume, and correction of acidosis were all associated with lower rates of delayed graft function and improved serum creatinine levels prior to organ recovery (151,158,271,272).…”

Section: Is There An Optimal Fluid Resuscitation Strategy To Improve mentioning

confidence: 96%

“…More recently, retrospective analysis of a prospectively collected dataset from a clinical trial (evaluating donor pretreatment with dopamine) of almost 500 patients from over 60 European transplant centers reported no difference in early post-kidney transplant outcomes in the group that received desmopressin therapy but superior 2-year allograft survival, especially in the subset that also received dopamine therapy (130,156). Other retrospective studies have similarly suggested benefit with regard to renal allograft function in association with donor desmopressin treatment (130,(156)(157)(158). Both AVP and desmopressin can be administered concurrently in the potential organ donor with significant hypernatremia and hypotension.…”

Section: How Should Avp Deficiency In the Organ Donor Be Treated?mentioning

confidence: 99%

“…Evidence is based on retrospective studies (157,158,277) with the exception of one prospective randomized trial (130). All common vasopressors-dopamine, dobutamine, phenylephrine, epinephrine, and norepinephrine-are used in the management of organ donors, but the first choice in vasopressors is inconsistent.…”

Section: What Is the Effect Of Vasopressors And Inotropic Agents On Kmentioning

confidence: 99%

“…However, one retrospective study identified epinephrine use as an independent factor for elevated creatinine levels prior to organ recovery (158) in organ donor management to treat both DI and hypotension, but published results of its use are not available. A recent large retrospective study demonstrated that the use of AVP resulted in increased organ procurement, including kidneys (134).…”

Section: What Is the Effect Of Vasopressors And Inotropic Agents On Kmentioning

confidence: 99%

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Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

280

150

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This document was developed through the collaborative efforts of the Society of Critical Care Medicine, the American College of Chest Physicians, and the Association of Organ Procurement Organizations. Under the auspices of these societies, a multidisciplinary, multi-institutional task force was convened, incorporating expertise in critical care medicine, organ donor management, and transplantation. Members of the task force were divided into 13 subcommittees, each focused on one of the following general or organ-specific areas: death determination using neurologic criteria, donation after circulatory death determination, authorization process, general contraindications to donation, hemodynamic management, endocrine dysfunction and hormone replacement therapy, pediatric donor management, cardiac donation, lung donation, liver donation, kidney donation, small bowel donation, and pancreas donation. Subcommittees were charged with generating a series of management-related questions related to their topic. For each question, subcommittees provided a summary of relevant literature and specific recommendations. The specific recommendations were approved by all members of the task force and then assembled into a complete document. Because the available literature was overwhelmingly comprised of observational studies and case series, representing low-quality evidence, a decision was made that the document would assume the form of a consensus statement rather than a formally graded guideline. The goal of this document is to provide critical care practitioners with essential information and practical recommendations related to management of the potential organ donor, based on the available literature and expert consensus.

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Section: Is There An Optimal Fluid Resuscitation Strategy To Improve mentioning

confidence: 96%

Section: How Should Avp Deficiency In the Organ Donor Be Treated?mentioning

confidence: 99%

Section: What Is the Effect Of Vasopressors And Inotropic Agents On Kmentioning

confidence: 99%

Section: What Is the Effect Of Vasopressors And Inotropic Agents On Kmentioning

confidence: 99%

See 2 more Smart Citations

Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

280

150

View full text Add to dashboard Cite

show abstract

“…First observed by Muruve et al [31] in a clinical trial with kidney transplants in 2001, an abrogation of IRI with longer brain death time prior to procurement was reported. Subsequently, various publications on this topic came to partially conflicting results [13,[31][32][33]. Nijboer et al [34] reported a large retrospective analysis of kidney transplantations (KTx) based on an extract of the Organ Procurement and Transplantation Network (OPTN) database within the USA, including 20 773 donor-recipient pairs during an 8-year period between 1994 and 2006.…”

Section: Clinical Impact Of Brain Death-mediated Injurymentioning

confidence: 99%