2011
DOI: 10.1186/1471-2458-11-s3-s6
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Impact of interventions to prevent and manage preeclampsia and eclampsia on stillbirths

Abstract: BackgroundPre-eclampsia and Eclampsia are relatively common complications of pregnancy, leading to considerable maternal and fetal mortality and morbidity. We sought to review the effect of aspirin, calcium supplementation, antihypertensive agents and magnesium sulphate on risk stillbirths.MethodsA systematic literature search was conducted to identify studies evaluating the above interventions. We used a standardized abstraction and grading format and performed meta-analyses where data were available from mor… Show more

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Cited by 44 publications
(41 citation statements)
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“…It also had a significant protective effect on maternal mortality and serious morbidity and preterm birth [22-24]. …”
Section: Summary Of Essential Interventions Applicable At All Levels:mentioning
confidence: 99%
“…It also had a significant protective effect on maternal mortality and serious morbidity and preterm birth [22-24]. …”
Section: Summary Of Essential Interventions Applicable At All Levels:mentioning
confidence: 99%
“…In a subsequent meta-analysis using CHERG methods, calcium supplementation during pregnancy was associated with an estimated 45% reduction in the risk of gestational hypertension (0·55, 0·36-0·85) and 59% in the risk of pre-eclampsia (0·41, 0·24-0·69). 23,48 Information on stillbirth outcomes was limited, but stillbirth has a known association with hypertensive disease of pregnancy and pre-eclampsia, 49 and therefore calcium supplementation in women with low baseline calcium intake was estimated to reduce the risk of stillbirth by 19%, although the reduction was not signifi cant (table 1). 23 …”
Section: Nutritional Interventions Before and During Pregnancymentioning
confidence: 99%
“…The experts suggested a 20% median reduction in each of antepartum stillbirths (IQR 10-30) and intrapartum stillbirths (10-40) from introduction of these interventions. 23 …”
Section: Prevention and Management Of Hypertensive Disease Of Pregnancymentioning
confidence: 99%
“…Los estados hipertensivos de la gestación persisten como la principal causa de muerte materna en los países pobres, siendo responsables de 63.000 muertes anuales y la mortalidad materna por preeclampsia es entre el 0% y 13.2% 16 . La presentación de esta última alteración es entre el 5% y 8% de las gestaciones y puede llevar a resultados perinatales adversos como bajo peso al nacer, prematuridad, muerte fetal y retardo del crecimiento intrauterino 17 . También es causa de secuelas permanentes en la mujer, como alteraciones neurológicas, hepáticas, renales o hematológicas 18 .…”
Section: -Temas Y Categorías Resultantesunclassified