This research work aimed to project and analyse climatic variability in the Hathmati River Basin that happens to be one of the most important tributaries of Western India using GCMs and RCMs. The analysis included a baseline period from 1980 to 2014 and future scenario (2050 s) under a representative concentration pathway (RCP4.5). Following the evaluation of bias correction methods, the distribution mapping and power transformation were used for temperature and precipitation projection, respectively. The 2050 s RCP4.5 simulations showed an increase in precipitation to 1,015.54 mm from 936.91 mm giving around 8.45% of increase in average precipitation. For temperature, the maximum temperature shows around 7.05% increase taking the average temperature to 34.21 from 33.97. The minimum temperature goes to 20.24 from 20.41 showing positive change of around 8.4%. The future precipitation and temperature change projected might worsen the water stress and probability of the occurrence severe events, and hence mitigation strategies and management options to reduce this negative impact should be encouraged.