Impact of Life and Family Background on Delayed Presentation to Hospital in Acute Stroke

Hagiwara, Yuta; Imai, Takeshi; Yamada, Koji; Sakurai, Kenzo; Atsumi, Chihiro; Tsuruoka, Atsushi; Mizukami, Heisuke; Sasaki, Naoshi; Akiyama, Hisanao; Hasegawa, Yasuhiro

doi:10.1016/j.jstrokecerebrovasdis.2013.05.034

Cited by 11 publications

(3 citation statements)

References 17 publications

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“…Most of our patients have national health insurance that covers stroke-related medical expenses including intravenous thrombolysis, this probably contributes to none of our patients mentioning cost consideration as a delay reason. Living in an elderly household or living alone was found to be significantly associated with delayed presentation of stroke patients [27], while in this study, only a small proportion of patients lived alone. Wake-up stroke and unknown stroke onset play a significant role in presentation delay, as shown in other studies [19,28].…”

Section: Discussioncontrasting

confidence: 66%

Characteristics and reasons for delayed presentation in acute ischemic stroke: single-centered study in Indonesia

Yang,

Hartanto

2024

Egypt J Neurol Psychiatry Neurosurg

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Background Effective therapy for acute ischemic stroke relies on timely intervention. We aimed to evaluate the factors associated with the onset-to-arrival time and delayed hospital presentation in acute ischemic stroke patients. Subjects with acute ischemic stroke in Bethesda Hospital Yogyakarta, Indonesia from March to June, 2023 were prospectively recruited. A questionnaire was used to collect the information by direct interviews. Prespecified variables were included in univariate and multivariable analyses to identify the predictors of delayed hospital presentation of more than 4.5 h. Results Among a total of 175 patients, 64.6% of the patients arrived at the hospital more than 4.5 h after the stroke onset. Only 3 (1.7%) patients were eligible and received intravenous thrombolysis. In multivariable analysis, monthly income of more than IDR 550,000 (OR, 4.22; 95% CI 1.47–12.17; p = 0.007), wake-up stroke or unknown stroke onset (OR vs. known onset, 0.17; 95% CI 0.05–0.56; p = 0.004), distance from location of stroke onset more than 9.45 km (OR, 3.13; 95% CI 1.41–6.92; p = 0.005) and no history of coronary artery disease or heart failure (OR vs. present history, 0.12; 95% CI 0.04–0.37; p = 0.000) were related to delayed hospital presentation. The most frequently mentioned reasons for the delay were waiting for spontaneous improvement at home and unawareness of the stroke symptoms. Conclusions There is an enormous disparity in stroke services between developed and developing countries. This study highlighted the need to increase public stroke symptoms awareness.

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Section: Discussioncontrasting

confidence: 66%

Characteristics and reasons for delayed presentation in acute ischemic stroke: single-centered study in Indonesia

Yang,

Hartanto

2024

Egypt J Neurol Psychiatry Neurosurg

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“…[17][18][19][20][21][22][23][24][25][26][27] In addition, stroke often damages the areas of the brain that control either the patient's perception of a problem or the patient's ability to communicate. [17][18][19][20][21][22][23][24][25][26][27] In addition, stroke often damages the areas of the brain that control either the patient's perception of a problem or the patient's ability to communicate.…”

Section: Key Pointsmentioning

confidence: 99%

Prehospital and Emergency Department Care of the Patient with Acute Stroke

Gensic¹,

Pancioli²

2016

Stroke

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“…The aging of population has been a growing problem in the worldwide, and aging society will be the destination of all countries. In Japan, the population over the age of 65 sums up to more than 20% of the total amount, which is the highest in the world and will continue to rise 1 . In the United States, individuals age 65 and older has increased by 18% just within the last decade and have estimated to become 79 million by the year 2040, making up 20% of the total U.S. population 2 .…”

Section: Introductionmentioning

confidence: 99%

Coccomyxa Gloeobotrydiformis Improves Learning and Memory in Intrinsic Aging Rats

Sun¹,

Jin²,

Dong

et al. 2015

Int. J. Biol. Sci.

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Declining in learning and memory is one of the most common and prominent problems during the aging process. Neurotransmitter changes, oxidative stress, mitochondrial dysfunction and abnormal signal transduction were considered to participate in this process. In the present study, we examined the effects of Coccomyxa gloeobotrydiformis (CGD) on learning and memory ability of intrinsic aging rats. As a result, CGD treated (50 mg/kg·d or 100 mg/kg ·d for a duration of 8 weeks) 22-month-old male rats, which have shown significant improvement on learning and spatial memory ability compared with control, which was evidently revealed in both the hidden platform tasks and probe trials. The following immunohistochemistry and Western blot experiments suggested that CGD could increase the content of Ach and thereby improve the function of the cholinergic neurons in the hippocampus, and therefore also improving learning and memory ability of the aged rats by acting as an anti-inflammatory agent. The effects of CGD on learning and memory might also have an association with the ERK/CREB signalling. The results above suggest that the naturally made drug CGD may have several great benefit as a multi-target drug in the process of prevention and/or treatment of age-dependent cognitive decline and aging process.

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Impact of Life and Family Background on Delayed Presentation to Hospital in Acute Stroke

Cited by 11 publications

References 17 publications

Characteristics and reasons for delayed presentation in acute ischemic stroke: single-centered study in Indonesia

Characteristics and reasons for delayed presentation in acute ischemic stroke: single-centered study in Indonesia

Prehospital and Emergency Department Care of the Patient with Acute Stroke

Coccomyxa Gloeobotrydiformis Improves Learning and Memory in Intrinsic Aging Rats

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