2005
DOI: 10.1016/j.jhin.2004.07.022
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Impact of local guidelines and an integrated dispensing system on antibiotic prophylaxis quality in a surgical centre

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Cited by 41 publications
(22 citation statements)
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“…[48][49][50] The use of standardized antimicrobial order sets, automatic stop-order programs, and educational initiatives has been shown to facilitate the adoption of guidelines for surgical antimicrobial prophylaxis. [51][52][53][54][55][56][57][58] …”
Section: Requirements For Effective Surgical Prophylaxismentioning
confidence: 99%
See 1 more Smart Citation
“…[48][49][50] The use of standardized antimicrobial order sets, automatic stop-order programs, and educational initiatives has been shown to facilitate the adoption of guidelines for surgical antimicrobial prophylaxis. [51][52][53][54][55][56][57][58] …”
Section: Requirements For Effective Surgical Prophylaxismentioning
confidence: 99%
“…Ideally, an antimicrobial agent for surgical prophylaxis should (1) prevent SSI, (2) prevent SSI-related morbidity and mortality, (3) reduce the duration and cost of health care (when the costs associated with the management of SSI are considered, the cost-effectiveness of prophylaxis becomes evident), 51,52 (4) produce no adverse effects, and (5) have no adverse consequences for the microbial flora of the patient or the hospital. 53 To achieve these goals, an antimicrobial agent should be (1) active against the pathogens most likely to contaminate the surgical site, (2) given in an appropriate dosage and at a time that ensures adequate serum and tissue concentrations during the period of potential contamination, (3) safe, and (4) administered for the shortest effective period to minimize adverse effects, the development of resistance, and costs.…”
Section: Common Principlesmentioning
confidence: 99%
“…In descriptive studies lacking a control group, stricter implementation of the existing antimicrobial prophylaxis protocols was associated with an increase in the appropriateness of antibiotic prophylaxis from approximately 50% to 95%-100%. 21,22 In Jordan in general and, specifically, in the Queen Alia Heart Institute (QAHI), in which the present study was conducted, antimicrobial prophylaxis in cardiac surgery is not governed either by national or by local guidelines. This problem is typical of other developing countries.…”
Section: Adherence To International Antimicrobial Prophylaxis Guidelimentioning
confidence: 99%
“…Some authors say that it is effective, others say that it is not, despite the fact that antibiotic prophylaxis against postoperative wound infections accounts for 30% of prescriptions for antibiotics in general hospitals, 6 and that the excessive and inappropriate use of antibiotics may lead to bacterial resistance and increase the economic burden of healthcare.…”
Section: Introductionmentioning
confidence: 99%