AODV (Ad hoc On‐Demand Distance Vector) is a well‐known routing protocol for wireless networks. Recently, Time Slotted Channel Hopping (TSCH) was proposed as a MAC layer protocol, specified in the IEEE 802.15.4e standard. As MAC layer protocols can impact the performance of protocols in the layers above, we examine the performance of AODV over TSCH and compare it with CSMA. We investigate using different metrics, such as latency, packet delivery rate, and energy consumption. We implemented AODV, as defined by the RFC 3561, using the embedded systems operational system Contiki‐NG, a well established platform for Low power and Lossy Networks (LLNs), and the Internet of things (IoT). Our results, running on the Cooja platform, show that TSCH can greatly improve the performance of AODV, achieving a packet delivery rate of almost 100%. Moreover, our results also show that TSCH consumes less energy than CSMA.