Impact of maternal substance use on offspring's cardiovascular health.

Janardhan, Nitya; Roy, Pritha Ghosh; Vyas, Arpita

doi:10.1016/j.taap.2022.116164

Cited by 2 publications

(1 citation statement)

References 85 publications

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“…The adverse environment during pregnancy can be divided into exogenous factors and maternal factors. It has been found that most of the adverse environmental factors can cross the placental barrier and directly affect embryonic or fetal development, such as polycyclic aromatic hydrocarbons, [4] particulate matter 2.5 (PM2.5), [5,6] dexamethasone, [7,8] heavy metals, [9,10] nicotine, [11,12] ethanol, [13] caffeine, [14,15] cocaine, [16,17] and opioids, [17][18][19] etc. Besides, some environmental factors that cannot cross the placental barrier can indirectly affect fetal development by disrupting the structure and function of the placenta, such as exposure to cobalt and chromium nanoparticles causing placental autophagic flow impairment and interleukin (IL)-6 release, which disrupts fetal astrocytes and neurons development.…”

Section: The Adverse Environment During Pregnancy Leads To the Occurr...mentioning

confidence: 99%

Placental biomarkers of fetal-originated diseases

Yu,

Chen,

Wang

2024

PRM

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Fetal-originated diseases refer to birth defects of offspring and multiple chronic diseases in adulthood caused by abnormal embryonic development. However, due to the vulnerability of the fetus/ neonate and technical limitations, it is very difficult to carry out effective development assessment and early warning of long-term diseases in the early stages of life. It is known that the placenta is the unique link between the mother and the fetus, and its role in the occurrence and progression of fetal-originated diseases cannot be ignored. Studies have found that a variety of adverse environmental factors (such as nanoparticle exposure) cannot pass through the placental barrier, but can lead to fetal dysplasia and multi-organ development programming changes by affecting placental development, and ultimately mediate the occurrence of fetal-originated diseases. Meanwhile, some environmental factors that can pass through the placental barrier can cause placenta-fetal co-exposure, resulting in similar signaling pathways and epigenetic changes. The placenta originates from the fetus and the mother, and its development is accompanied by changes in indicators that can be objectively and quantitatively detected. These factors can be used as a biomarker to assess maternal exposure, and placental function, and to predict the developmental status and long-term disease susceptibility of offspring. To date, researchers have discovered a variety of potential placental biomarkers, and show promising application prospects. This paper reviews the recent research on placenta-related mechanisms leading to fetal-originated diseases and placental biomarkers, to provide the theoretical and experimental basis for early warning, prevention, and treatment of fetal-originated diseases.

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Section: The Adverse Environment During Pregnancy Leads To the Occurr...mentioning

confidence: 99%

Placental biomarkers of fetal-originated diseases

Yu,

Chen,

Wang

2024

PRM

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An Overview of Fetal Alcohol Spectrum Disorders (FASDs)

Olson,

Chew,

Feller-Mende

2023

Advances in Educational Marketing, Administration, and Leadership

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Fetal alcohol spectrum disorders are prevalent and impact student functioning in a variety of ways. This chapter focuses on providing school counselors with the information needed to develop an understanding of the history and prevalence of FASDs, diagnostic considerations, and terminology, the impact of prenatal alcohol exposure, and a framework for providing FASD-informed care for their students. The FASD-informed approach to intervention includes methods for identifying students with FASD. Considerations of the student's individual strengths and weaknesses are reviewed as are considerations of the student's environmental influences, cultural and linguistic differences, and family involvement. Strategies for collaborating and consulting with others such as family members, educators, other school-based providers, medical practitioners, and community providers are discussed. The importance of accommodations and how to select appropriate interventions are presented and resources are provided.

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Impact of maternal substance use on offspring's cardiovascular health.

Cited by 2 publications

References 85 publications

Placental biomarkers of fetal-originated diseases

Placental biomarkers of fetal-originated diseases

An Overview of Fetal Alcohol Spectrum Disorders (FASDs)

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